Acyltransferase
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Acyltransferase 関連製品 (203)
関連製品 (203)
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Aphadilactone C
0 Images製品番号: HY-N7281CAS 番号: 1522004-70-1Aphadilactone C is a potent and selective DGAT-1 inhibitor with an IC50 of 0.46 μM. Aphadilactone C shows significant antimalarial activities with an IC50 value of 170 nM.
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2-Fluoropalmitic acid (Standard)
0 Images製品番号: HY-117651RCAS 番号: 16518-94-8Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM.
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ACAT-IN-5
0 Images製品番号: HY-139022CAS 番号: 199983-93-2ACAT-IN-5 (example 19) is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor. ACAT-IN-5 inhibits NF-κB mediated transcription.
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16-NBD-16:0 Coenzyme A triammonium
0 Images16-NBD-16:0 Coenzyme A triammonium can be used as a substrate to measure the in vitro activity of other Acyltransferase .
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NTE-122 dihydrochloride
0 Images製品番号: HY-121762CAS 番号: 166967-84-6NTE-122 (dihydrochloride) is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with the IC50 in liver and aorta of cholesterol-fed rabbits of 7.6nM, 4.4nM and 9.6 nM, respectively, that plays an important role in atherosclerosis.
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PD 128042 (Standard)
0 Images別名: CI 976 (Standard)PD 128042 (Standard) is the analytical standard of PD 128042. This product is intended for research and analytical applications. PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase) with an IC50s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC50=15 μM). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway.
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Nevanimibe hydrochloride (Standard)
0 Images別名: PD-132301 hydrochloride (Standard); ATR101 hydrochloride (Standard)Nevanimibe hydrochloride (Standard) is the analytical standard of Nevanimibe hydrochloride. This product is intended for research and analytical applications. Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer.
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RHC 80267 (Standard)
0 Images製品番号: HY-107416RCAS 番号: 83654-05-1別名: U-57908 (Standard)RHC 80267 (Standard) is the analytical standard of RHC 80267 (HY-107416). This product is intended for research and analytical applications. RHC 80267 (U-57908) is a potent and selective inhibitor of diacylglycerol lipase (DAGL) (with IC50 of 4 μM in canine platelets). RHC-80267 inhibits cholinesterase activity with an IC50 of 4 μM, thereby enhancing the relaxation evoked by acetylcholine. RHC 80267 also inhibits COX and the hydrolysis of phosphatidylcholine (PC).
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JNJ-DGAT2-A (Standard)
0 Images製品番号: HY-110381RCAS 番号: 1962931-71-0JNJ-DGAT2-A (Standard) is the analytical standard of JNJ-DGAT2-A (HY-110381). This product is intended for research and analytical applications. JNJ-DGAT2-A is a selective diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 value of 0.14 μM in human DGAT2-expressing Sf9 insect cell membranes. JNJ-DGAT2-A can be used for the research of triglyceride (TG) synthesis.
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JTP-103237
0 Images製品番号: HY-135505CAS 番号: 1883864-16-1
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MGAT2-IN-7
0 Images製品番号: HY-181564CAS 番号: 3115123-06-0MGAT2-IN-7 is an orally active monoacylglycerol acyltransferase 2 (MGAT2) inhibitor. MGAT2-IN-7 is used for research on obesity and metabolic dysfunction-associated steatotic liver disease (MASLD).
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Melinamide (Standard)
0 Images製品番号: HY-101722RCAS 番号: 14417-88-0別名: AC 223 (Standard); DL-N-(α-Methylbenzyl)linoleamide (Standard)Melinamide (Standard) is the analytical standard of Melinamide. This product is intended for research and analytical applications. Melinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC50 of 20.9 μM.
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Glisoprenin A
0 Images製品番号: HY-N14525CAS 番号: 144376-62-5Glisoprenin A is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea.
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VULM 1457 (Standard)
0 Images製品番号: HY-107571RCAS 番号: 228544-65-8VULM 1457 (Standard) is the analytical standard of VULM 1457 (HY-107571). This product is intended for research and analytical applications. VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia.
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PF-06424439 methanesulfonate (Standard)
0 Images製品番号: HY-108341ARCAS 番号: 1469284-79-4PF-06424439 methanesulfonate (Standard) is the analytical standard of PF-06424439 (methanesulfonate) (HY-108341A). This product is intended for research and analytical applications. PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate.
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Glisoprenin D
0 Images製品番号: HY-N14813CAS 番号: 205594-89-4Glisoprenin D is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea.
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JNJ-DGAT1-A
0 Images製品番号: HY-16266CAS 番号: 1092067-85-0
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LRAT-IN-1
0 Images製品番号: HY-169085CAS 番号: 2820064-05-7LRAT-IN-1 (compound 1) is a retinol acyltransferase (LRAT) inhibitor (IC50=21.1 μM). LRAT-IN-1 provides anti-aging effects by inhibiting the esterification of retinol to form retinol esters, increasing the available retinol in the skin. Research on LRAT-IN-1 as an anti-aging ingredient in cosmetics.
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Glisoprenin C
0 Images製品番号: HY-N14574CAS 番号: 205594-88-3Glisoprenin C is a cholesterol acyltransferase (ACAT) inhibitor, and it can inhibit the formation of Appressorium on the hydrophobic surface of Magnaporthegrisea.
