Acyltransferase
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Acyltransferase Produits associés (202)
Produits associés (202)
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BAY 74-4113
0 ImagesCat. No.: HY-16088CAS No.: 791593-56-1
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(E)-Hyzetimibe
0 ImagesCat. No.: HY-107176CAS No.: 1266548-75-7Synonyms: (E)-HS-25(E)-Hyzetimibe ((E)-HS-25) (Compound I-1Z) is the trans isomer of Hyzetimibe (HY-107176A), a cholesterol-lowering agent. (E)-Hyzetimibe has cholesterol acyltransferase (ACTA) inhibitory activity, but its cholesterol-lowering effect is relatively weak. (E)-Hyzetimibe can inhibit the entry of hepatitis C virus (HCV) into host cells, and it has a synergistic effect when used in combination with interferon-α. (E)-Hyzetimibe can be used for the study of HCV infection.
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ACAT-IN-9
0 ImagesCat. No.: HY-139026CAS No.: 199984-40-2ACAT-IN-9 is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor extracted from patent EP1236468A1, example 207. ACAT-IN-9 inhibits NF-κB mediated transcription.
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ACAT-IN-4
0 ImagesCat. No.: HY-139021CAS No.: 454203-56-6ACAT-IN-4 (Example 208) is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor. ACAT-IN-4 inhibits NF-κB mediated transcription.
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1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
![1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone](https://file.medchemexpress.com/product_pic/hy-n9530.gif "Click to View 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone Product Detail")
0 ImagesCat. No.: HY-N9530CAS No.: 120693-53-01-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a quinolone alkaloid, is a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, with IC50s of 20.1 μM and 34.1 μM, respectively. 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone shows potent anti-Helicobacter pylori activity with the MIC of 10 μg/mL.
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ACAT-IN-10 dihydrochloride
0 ImagesCat. No.: HY-139027ACAS No.: 199983-77-2ACAT-IN-10 dihydrochloride is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor extracted from patent EP1236468A1, example 197. ACAT-IN-10 dihydrochloride weakly inhibits NF-κB mediated transcription.
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Enniatin A-13C36
0 ImagesCat. No.: HY-N6702SEnniatin A-13C36 is the 13C-labeled Enniatin A (HY-N6702). Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes.
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Bay-02752
0 ImagesCat. No.: HY-123666CAS No.: 78991-74-9Synonyms: Bay o 2752Bay-02752 (Bay o 2752) is a lipid-lowering agent. Bay-02752 inhibits acyl-CoA activity in liver microsomes (IC50 = 0.95 μg/mL). Bay-02752 inhibits intestinal cholesterol absorption in rats. Bay-02752 inhibits gallstone formation in hamsters.
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ACAT-IN-6
0 ImagesCat. No.: HY-139023CAS No.: 454203-45-3ACAT-IN-6 is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor extracted from patent EP1236468A1, example 200. ACAT-IN-6 potently inhibits NF-κB mediated transcription.
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AS-183
0 ImagesCat. No.: HY-129340CAS No.: 147317-12-2AS-183 is an inhibitor of cholesterol acyltransferase (ACAT) (IC50=0.94 µM). AS-183 also inhibits the formation of cholesterol esters in HepG2, CaCo2 and THP-1 cells with IC50 values of 18.1, 25.5 and 34.5 µM, respectively. AS-183 can be used in the study of atherosclerosis and hypercholesterolemia.
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ACAT-IN-3
0 ImagesCat. No.: HY-139020CAS No.: 454203-25-9ACAT-IN-3 is an acyl-Coenzyme A:cholesterol acyltransferase (ACAT) inhibitor. ACAT-IN-3 inhibits NF-κB mediated transcription.
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TA-7552
0 ImagesCat. No.: HY-100253CAS No.: 104756-72-1TA-7552 is a potent cholesterol-lowering agent.
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BW813U
0 ImagesCat. No.: HY-183572CAS No.: 774142-74-4BW813U is a blood-brain barrier-permeable choline acetyltransferase (ChAT) inhibitor. BW813U reduces acetylcholine secretion, decreases cancer cell viability, and slows tumor growth rate. BW813U alters reference memory and causes working memory dysfunction. BW813U shows a synergistic effect with age factors in memory deficits of rats. BW813U can be used in studies related to Alzheimer's disease and lung cancer.
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IONIS-DGAT 2Rx sodium scrambled negative control
0 ImagesCat. No.: HY-159698BIONIS-DGAT 2Rx sodium scrambled negative control is the sequence scrambled negative control of IONIS-DGAT 2Rx sodium.
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Enniatin B1-13C34
0 ImagesCat. No.: HY-N3807SEnniatin B1-13C34 is the 13C-labeled Enniatin B1 (HY-N3807). Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 73 μM in an enzyme assay using rat liver microsomes. Enniatin B1 crosss the blood-brain barrier. Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation.
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JTT-553
0 ImagesCat. No.: HY-123765CAS No.: 701232-94-2JTT-553 is a DGAT1 inhibitor (IC50: 2.38 nM). JTT-553 reduces plasma concentrations of glucose, insulin, non-esterified fatty acids (NEFA), total cholesterol (TC), and hepatic triglycerides (TG). JTT-553 improves insulin-dependent glucose uptake and glucose intolerance in adipose tissue of DIO mice. JTT-553 reduces TNF-α mRNA levels and increases GLUT4 mRNA levels in adipose tissue of KK-Ay mice. JTT-553 improves adipose tissue insulin resistance and systemic glucose metabolism by reducing body weight. JTT-553 can be used in the study of obesity and type 2 diabetes mellitus (T2DM).
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β-Glucogallin-tetrakisgalloylglucose O-galloyltransferase
0 ImagesCat. No.: HY-E71304Aβ-glucogallin-tetrakisgalloylglucose O-galloyltransferase (EC 2.3.1.143) belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups.
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Lateritin
0 ImagesCat. No.: HY-121407CAS No.: 172721-98-1Lateritin is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), isolated from the mycelial cake of Gibberella lateritium IFO 7188. Lateritin also inhibits the growth of a mini-panel of human cancer cell lines, gram-positive bacteria, and Candida albicans.
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IONIS-DGAT 2Rx
0 ImagesCat. No.: HY-159698CAS No.: 2091332-22-6Synonyms: ISIS 484137; ION-224IONIS-DGAT 2Rx (ION-224) is a DGAT2 inhibitor, which is promising for research of atherosclerosis.
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Diacylglycerol acyltransferase inhibitor-1
0 ImagesCat. No.: HY-112851CAS No.: 1610800-25-3
