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Art. -Nr.: HY-16088

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BAY 74-4113

BAY 74-4113 is a DGAT1 inhibitor (IC₅₀: 72 nM). BAY 74-4113 can be used in obesity research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 791593-56-1
Formel: C₂₆H₂₀F₂N₂O₃S
Molecular Weight:478.51

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

BAY 74-4113 Chemical Structure

CAS. Nr.: 791593-56-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

BAY 74-4113 is a DGAT1 inhibitor (IC₅₀: 72 nM). BAY 74-4113 can be used in obesity research^[1]^[2].

Alle Acyltransferase Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
Sf9	IC₅₀	73 nM Compound: 3, BAY-744113	Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scintillation counter Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scintillation counter	[PMID: 21868220]

Chemical Information

CAS. Nr. 791593-56-1
Molecular Weight 478.51
Formel C₂₆H₂₀F₂N₂O₃S
SMILES

FC1=CC=C2C(SC(NC3=C(C=C(C4=CC=C(C=C4)C([C@H]5[C@@H](CCC5)C(O)=O)=O)C=C3)F)=N2)=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Roger Smith, et al. Preparation and use of aryl alkyl acid derivatives for the treatment of obesity. US7091228B2. Bayer Pharmaceuticals Corp. 2004-05-06.

[2]. Kandre S, et al. Synthesis and evaluation of cyclohexane carboxylic acid head group containing isoxazole and thiazole analogs as DGAT1 inhibitors. Eur J Med Chem. 2014 May 22;79:203-15. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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