Enniatin A
Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes.
For research use only. We do not sell to patients.
- CAS No.: 2503-13-1
- Formula: C36H63N3O9
- Molecular Weight:681.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-N6704
Enniatin A1Apoptosis Inducer -
HY-N3807
Enniatin B1ACAT Inhibitor -
HY-129591
Paraherquamide AAnthelmintic -
HY-N7071A
Maduramicin ammoniumAntibiotic -
HY-N6706
Enniatin complexIonophore -
HY-N10220
Paraherquamide EInsecticide -
HY-N7071
MaduramicinAnticoccidial Agent -
HY-N7071AR
Maduramicin ammonium (Standard)Anticoccidial Agent
Biological Activity
Description
IC50 & Target
[1]|
ACAT |
In Vitro
Enniatin A exhibits cytotoxic effects in HeLa cell lines with IC50s of 1.15 μM concentration for 24 h and 0.57 μM concentration for 48 h[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2503-13-1
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Molecular Weight 681.90
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Formula C36H63N3O9
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SMILES
CC[C@@H]([C@]1([H])N(C([C@H](OC(C(N(C([C@@H](C(C)C)OC([C@@]([C@@H](C)CC)([H])N(C)C([C@](C(C)C)([H])OC1=O)=O)=O)=O)C)[C@@H](C)CC)=O)C(C)C)=O)C)C
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Structure Classification
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Initial Source
Fusarium sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Tomoda H, et al. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J Antibiot (Tokyo). 1992 Oct;45(10):1626-32. [Content Brief]
[2]. Mamur S, et al. Assessment of cytotoxic and genotoxic effects of enniatin-A in vitro. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Aug;35(8):1633-1644. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Enniatin A Related Classifications
HY-N6702 Related Classifications
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