1. Others
  2. Others
  3. TA-7552

TA-7552 

Cat. No.: HY-100253
Handling Instructions

TA-7552 is a potent cholesterol-lowering agent.

For research use only. We do not sell to patients.

TA-7552 Chemical Structure

TA-7552 Chemical Structure

CAS No. : 104756-72-1

Size Price Stock
1 mg USD 751 Get quote
5 mg USD 1202 Get quote
10 mg USD 1923 Get quote

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

TA-7552 is a potent cholesterol-lowering agent.

In Vivo

TA-7552 is a potent cholesterol-lowering agent. When TA-7552 is mixed with unsupplemented CLEA CE-2 powder in a concentration of 0.05% and administered to rats for 7 days, TA-7552 does not reduce the normal level of serum cholesterol. The hypocholesterolemic effect of TA-7552 is apparent at the lowest concentration (0.01%) of the drug in the diet, corresponding to a daily dose of ~10 mg/kg body weight, and maximal at the highest concentration of 0.2% TA-7552, lowering serum total cholesterol by 72% while elevating serum HDL cholesterol by 88%. TA-7552 also dose dependently suppresses this rise of hepatic cholesterol, and its lowering rate at the maximal dose is 90%[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Animal Administration
[1]

Male Sprague-Dawley rats (4 weeks of age) are used in this experiment. In the mechanism study, rats are divided into two or three groups of 4 to 6 animals so that the mean body weight, which varies from 210 g to 330 g, is similar between the groups. The experimental groups are treated with TA-7552 (0.1% in CE-2 powder) or cholestyramine (5% in CE-2 powder) by feeding the diet ad libitum for a period of time; The control groups are fed CE-2 powder. When the feces are collected, the animals are individually housed in a metabolic cage, and the collected feces are lyophylized and stored at -20°C[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

486.47

Formula

C₂₅H₂₆O₁₀

CAS No.

104756-72-1

SMILES

O=C(C1=C(C(OC)=O)C(C2=CC=C(OC)C(OC)=C2)=C3C(OC)=C(OC)C(OC)=CC3=C1O)OC

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
TA-7552
Cat. No.:
HY-100253
Quantity:

TA-7552

Cat. No.: HY-100253