E3 Ligase Ligand-Linker Conjugates Ligand
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(E)-JP-2-196 TFA
0 ImagesCat. No.: HY-W854844ACAS No.: 3065021-33-9JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be used to synthesize molecular glue degraders.
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(S,R,S)-AHPC-Bromooctanoic acid
0 ImagesCat. No.: HY-179435CAS No.: 2408342-03-8Synonyms: VH032-NH-Bromooctanoic acid(S,R,S)-AHPC-Bromooctanoic acid is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding linker (HY-W007700). (S,R,S)-AHPC-Bromooctanoic acid can serve as VHL (von Hippel-Lindau) ligand to recruit the VHL protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
