1. Signaling Pathways
  2. Epigenetics
  3. Epigenetic Reader Domain
  4. BRPF2 Isoform
  5. BRPF2 Inhibitor

BRPF2 Inhibitor

BRPF2 Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-107424
    BAY-299
    Inhibitor 99.24%
    BAY-299 is a very potent, dual inhibitor with IC50s of 67 nM for BRPF2 bromodomains (BD), 8 nM for TAF1 BD2, and 106 nM for TAF1L BD2.
  • HY-100729
    GSK9311
    Inhibitor 99.52%
    GSK9311, a less active analogue of GSK6853, can be used as a negative control.
  • HY-101121
    NI-42
    Inhibitor 99.79%
    NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins.
  • HY-100729A
    GSK9311 hydrochloride
    Inhibitor
    GSK9311 hydrochloride, a less active analogue of GSK6853, can be used as a negative control.