Fungal Inhibitor

D13, an Acylhydrazones derivative, possesses antifungal activity. D13 is effective against murine sporotrichosis.

Ametoctradin (Standard) is the analytical standard of Ametoctradin. This product is intended for research and analytical applications. Ametoctradin is a potent Qo site inhibitor of bc1 complex in mitochondrial respiration. Ametoctradin is a highly selective and effective Oomycete-specific fungicide that can be used against late blight and downy mildews.

Prothioconazole (Standard) is the analytical standard of Prothioconazole. This product is intended for research and analytical applications. Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor.

Haliangicin B has anti-filamentous fungi activity, and it also has effect on oomycetes, but has no antibacterial activity.

Epelmycin E has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin.

Terrestribisamide ((E)-N,N′-Diferuloylputrescine) can be isolated from dried fruits of Tribulus terrestris. Terrestribisamide has antibacterial, antifungal, antioxidant, anticancer effects.

Pneumocandin C0 is the isomer of Pneumocandin B0 (HY-17578) with antifungal activity, which is found by carrying out fermentations of Glarea lozoyensis at a high residual fructose concentration.

Methyl 3-(2-nitrophenyl) acrylate is an antifungal agent. Methyl 3-(2-nitrophenyl) acrylate exhibits activity against Candida albicans strains. Methyl 3-(2-nitrophenyl) acrylate can be used in research related to Candida albicans infections.

BHBM (compound 1) is an aromatic acylhydrazone antifungal agent with high bactericidal activity against Cryptococcus neoformans.

YZK-C22, containing a 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole skeleton, is a fungicide lead compound with broad-spectrum fungicidal activity.

Neocopiamycin B is found in the strain of Str. hygroscopicus var. crystallogenes. Neocopiamycin B has antifungal activity.

Pyraoxystrobin is a QoI fungicide, with an EC₅₀ of 0.0094 μg/mL for M. oryzae isolates. Pyraoxystrobin can be used for the research of M. oryzae in rice fields.

Group II intron-IN-1 (Compound 1) is an inhibitor of fungal Group II introns, with an IC₅₀ of 3 μM. Group II intron-IN-1 can be used for research on infections caused by fungi such as Candida.

Giparmen is an anti-tubercular agent. Giparmen is promising for research of fungal infections, particularly Candida.

Bis(4-morpholinyl)methane (N,N'-Methylene-bis-morpholine) is a broad-spectrum, slow-release formaldehyde-based fungicide. Bis(4-morpholinyl)methane inhibits the growth and reproduction of microorganisms, and prevents spoilage and odor generation in humid environments. Bis(4-morpholinyl)methane serves as a preservative for natural rubber latex.

Antifungal agent 89 (compound 28) is a antifungal agent against Cryptococcus neoformans with minimum inhibitory concentration value ranging from 0.8 to 52.17 μM.

Epoformin, is a fungal cyclohexene epoxide that can be isolated from Diplodia quercivora. Epoformin is an antibiotic and exhibits weak inhibitory activity against rye seedling sheath growth. Epoformin exhibits antifungal activity, inhibits Phytophthora cinnamomi and Phytophthora plurivora.

SDH-IN-40 (compound A7) is a succinate dehydrogenase inhibitor (SDHI). SDH-IN-40 exhibits strong inhibitory effects on F. graminearum (IC₅₀ = 34.33 μM). SDH-IN-40 can be used for research on fungal infections.

Epelmycin A has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin.

ECDG is a small-molecule compound dependent on α-ketoglutarate/Fe²⁺ that participates in the biosynthesis of echinocandins. ECDG is involved in the targeted transport of glucose, and can be used for PET imaging after labeling with radioactive atoms. ECDG increases blood glucose levels in rats, undergoes cellular uptake mediated by D-glucose, localizes in ischemic viable myocardial tissue, and accumulates in the synovial space of rheumatoid arthritis. ECDG can be used in research related to candidiasis, glucose metabolism disorders, fungal infections, myocardial ischemia and rheumatoid arthritis.