2. Signaling Pathways
  3. PROTAC
  4. PROTACs

PROTACs

PROTACs

Related Products

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PROTAC (PROteolysis-TArgeting Chimera) is a heterobifunctional nanomolecule containing two different ligands, ligand for ubiquitin E3 and ligand for target protein. The two parts are connected by linker to form a "three-unit" polymer, target protein ligand-linker-E3 ligase ligand. Building blocks of PROTAC molecules include PROTAC Linker, Ligand for Target Protein for PROTAC, Ligand for E3 Ligase, E3 Ligase Ligand-Linker Conjugate, Target Protein Ligand-Linker Conjugate, etc.

PROTACs Isoform Specific Products:

PROTACs Isoform Comparison
Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-103633R
    PROTAC BET Degrader-1 (Standard) 2093386-22-0
    PROTAC BET Degrader-1 (Standard) is the analytical standard of PROTAC BET Degrader-1 (HY-103633). This product is intended for research and analytical applications. PROTAC BET Degrader-1 is a PROTAC connected by ligands for Cereblon and BET, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration.
    PROTAC BET Degrader-1 (Standard)
  • HY-174856
    PROTAC HBeAg degrader-1
    PROTAC HBeAg degrader-1 is a PROTAC targeting degradation agent for HBeAg. PROTAC HBeAg degrader-1 recruits the VHL E3 ligase but degrades HBV protein HBeAg through VHL-independent mechanism. PROTAC HBeAg degrader-1 decreases levels of secreted and intracellular HBeAg. PROTAC HBeAg degrader-1 can be used for the research of hepatitis B virus (HBV).
    PROTAC HBeAg degrader-1
  • HY-161806
    ZXH-8-004
    ZXH-8-004 (2-12-2-deg) is a potent DENV E PROTAC degrader with an DC50 value of 0.21 µM. ZXH-8-004 shows exhibit antiviral potencies (Blue: E3 ligase (HY-103596), Black: linker (HY-42149); Pink: DENV E ligand (HY-161807)).
    ZXH-8-004
  • HY-185102
    ZBP1 PROTAC-1
    ZBP1 PROTAC-1 (2a+aptamer) is a Z-DNA binding protein 1 (ZBP1) PROTAC. ZBP1 PROTAC-1 consists of a DNA aptamer (specifically binds to ZBP1) and an E3 enzyme-recruiting unit. ZBP1 PROTAC-1 combines the high specificity of DNA aptamers with the degradation-inducing capabilities of PROTACs, providing a powerful tool for targeted protein degradation.
    ZBP1 PROTAC-1
  • HY-159607A
    PRT3789 epimer 3023568-80-8 98.83%
    PRT3789 epimer is an epimer of PRT3789 (HY-159607). PRT3789 is a selective SMARCA2 PROTAC degrader.
    PRT3789 epimer
Cat. No. Product Name / Synonyms Application Reactivity
PROTACs Isoform Comparison

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