1. Metabolic Enzyme/Protease
    PROTAC
  2. E1/E2/E3 Enzyme
    PROTAC

Homo-PROTAC cereblon degrader 1 

Cat. No.: HY-111594
Handling Instructions

Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.

For research use only. We do not sell to patients.

Homo-PROTAC cereblon degrader 1 Chemical Structure

Homo-PROTAC cereblon degrader 1 Chemical Structure

CAS No. : 2244520-98-5

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5 mg USD 900 Get quote
10 mg USD 1500 Get quote

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3[1].

IC50 & Target

Celeblon[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5137 mL 7.5685 mL 15.1371 mL
5 mM 0.3027 mL 1.5137 mL 3.0274 mL
10 mM 0.1514 mL 0.7569 mL 1.5137 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

660.63

Formula

C₃₂H₃₂N₆O₁₀

CAS No.

2244520-98-5

SMILES

O=C(N1C2CCC(NC2=O)=O)C3=CC=CC(NCCOCCOCCNC4=C5C(C(N(C6CCC(NC6=O)=O)C5=O)=O)=CC=C4)=C3C1=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Homo-PROTAC cereblon degrader 1
Cat. No.:
HY-111594
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Homo-PROTAC cereblon degrader 1

Cat. No.: HY-111594