PROTAC Vif degrader-1
PROTAC Vif degrader-1 (Compound L15) is a Vif PROTAC degrader. PROTAC Vif degrader-1 has antiviral activity against HIV-1 (EC50: 33.35 μM against HIV-1IIIB).
(Pink: HIV ligand (HY-163852); Blue: Cereblon ligand (HY-10984); Black: linker).
For research use only. We do not sell to patients.
- Formula: C41H41N7O12S
- Molecular Weight:855.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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HIV (IIIB) 33.35 μM (EC50) |
PROTAC Vif degrader-1 inhibits the replication of different wild-type HIV-1 strains in PBMCs (EC50: 10.53 μM and 8.76 μM for HIV-1kiz002 and HIV-1WAN respectively), with low cytotoxicity (CC50: > 200 µM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 855.87
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Formula C41H41N7O12S
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SMILES
COC1=CC=C(C=C1NC(C2=C(C=CC=C2SC3=CC=C(C=C3)[N+]([O-])=O)N)=O)OCC(NCCOCCOCCNC4=C5C(N(C(C5=CC=C4)=O)C6CCC(NC6=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC Vif degrader-1 Related Classifications
HY-163851 Related Classifications
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