PROTAC LRRK2 Degrader-2
PROTAC LRRK2 Degrader-2 is a PROTAC-based degrader targeting LRRK2 with a DC50 of 0.14 nM. PROTAC LRRK2 Degrader-2 recruits LRRK2 or its mutants to the cereblon E3 ubiquitin ligase, thereby mediating the targeted ubiquitination and subsequent proteasomal degradation of LRRK2. PROTAC LRRK2 Degrader-2 can be used in research related to Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 3080678-93-6
- Formula: C43H53N11O5
- Molecular Weight:803.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cereblon |
Chemical Information
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CAS No. 3080678-93-6
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Molecular Weight 803.95
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Formula C43H53N11O5
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SMILES
O=C1N(C2C(NC(CC2)=O)=O)C3=CC=C(N4CCC(CC4)O[C@@H]5CC[C@H](CC5)CN6CCN(C7=NC=NC(C(C8=C9)=NNC8=CN=C9OC%10(CC%10)C)=C7)CC6)C=C3N1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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