Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2533)
Related Products (2533)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Deferitazole
0 ImagesCat. No.: HY-101672CAS No.: 945635-15-4Synonyms: FBS 0701Deferitazole (FBS 0701) is an orally active iron chelator. Deferitazole shows antimalarial activity and Can be used for study of malaria .
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Cyclobenzaprine-d3-1 hydrochloride
0 ImagesCat. No.: HY-B0740S3CAS No.: 2712897-38-4Synonyms: MK130-d3-1 hydrochlorideCyclobenzaprine-d3-1 hydrochloride (MK130-d3-1 hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride (HY-B0740). Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases
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CpCDPK1/TgCDPK1-IN-1
0 ImagesCat. No.: HY-128397CAS No.: 1092788-23-2
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Carbendazimb-d3
0 ImagesCat. No.: HY-13582S1CAS No.: 1255507-88-0Carbendazimb-d3 is the deuterium labeled Carbendazimb (HY-13582). Carbendazim is a potent and orally active broad-spectrum?benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria,?Fusarium?and?Sclerotina. Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma.
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Antimalarial agent 12
0 ImagesCat. No.: HY-143487CAS No.: 2715225-58-2Antimalarial agent 12 (compound R-3b) is a potent antimalarial agent. Antimalarial agent 12 shows growth inhibition on P. falciparum Dd2 Strain (EC50=155 nM), 3D7 strain (EC50=136 nM). Antimalarial agent 12 has CC50 values of 10,000 to 50,000 nM for HEK-293 and hPHep cell lines. Antimalarial agent 12 has a MIC of >250,000 nM for Escherichia coli.
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Antileishmanial agent-31
0 ImagesCat. No.: HY-170358CAS No.: 861382-34-5Antileishmanial agent-31 (Compound p1) is a pyrazole derivative. Antileishmanial agent-31 has anti-leishmania activity with an IC50 of 35.53 μg/mL. In addition, Antileishmanial agent-31 has high stability. Antileishmanial agent-31 can be used for anti-leishmaniasis research.
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Atropine oxide
0 ImagesAtropine Oxide (Atropine oxidation), a derivative of Atropine, acts as a competitive antagonist to the muscarinic acetylcholine receptors M1, M2, M3, M4, and M5, and is utilized in the treatment of specific nerve agent and pesticide poisonings.
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Sulcatone-d5
0 ImagesCat. No.: HY-W782193CAS No.: 55320-91-7Synonyms: 6-Methyl-5-hepten-2-one-d5Sulcatone-d5 (6-Methyl-5-hepten-2-one-d5) is the deuterium labeled Sulcatone (HY-W010435). Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis.
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Stemonae extract
0 ImagesCat. No.: HY-N19959Stemonae Extract, extracted from the rhizome of Radix Stemonae, has antitussive, antituberculosis, antibacterial, antifungal, and antiparasitic effects.
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Picrolonic acid
0 ImagesPicrolonic acid is a nematode hatching agent and bacterial frameshift mutagen. Picrolonic acid induces egg hatching in various nematodes. Picrolonic acid induces frameshift mutations in Salmonella. Picrolonic acid preferentially inhibits the growth of DNA polymerase-deficient E. coli . Picrolonic acid also serves as an analytical reagent for the determination of calcium, magnesium, lead, strontium, and thorium, and for the analysis of alkaloids, tryptophan, and phenylalanine. Picrolonic acid is used in research related to bacterial and parasitic infections.
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AGPV
0 ImagesCat. No.: HY-P3425CAS No.: 154485-78-6AGPV, a tetrapeptide, has the potential for prevention of schistosome parasite infection research.
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Cyclomarin A
0 ImagesCat. No.: HY-P6300CAS No.: 169062-92-4Cyclomarin A is an antibacterial agent with a Kd of 2.3 nM against Mycobacterium tuberculosis ClpC1, a Kd of 2.2 nM against ClpC2, and an IC50 of 0.004 μM against Plasmodium falciparum PfAp3Aase. Cyclomarin A binds to the N-terminal domain of ClpC1, stimulates ATPase and proteolytic activities, dysregulates proteolysis, and induces proteome imbalance; it also binds to ClpC2 and upregulates its transcription level. Cyclomarin A binds to PfAp3Aase in dimeric form, blocks the substrate-binding pathway, inhibits the growth of Plasmodium falciparum in the erythrocytic stage, and shows no activity against human cells. Cyclomarin A exhibits moderate cytotoxicity against a variety of cancer cell lines. Cyclomarin A can serve as a lead compound for the development of Homo-BacPROTAC. Cyclomarin A is applicable to research related to tuberculosis and malaria.
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P-orlandin
0 ImagesCat. No.: HY-N10194CAS No.: 1407546-21-7
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SCYX-6759
0 ImagesCat. No.: HY-111906CAS No.: 1222509-12-7SCYX-6759 is an orally active, blood-brain barrier permeable anti-T. brucei agent. SCYX-6759 inhibits cytochrome P450 (IC50s: 30.3, 30.6, 47.4 μM for 2D6, 2C9, 2C19, respectively.) SCYX-6759 exhibits potent activity against T. b. brucei 427, T. b. rhodesiense STIB900, and T. b. gambiense STIB930, with IC50s of 0.07, 0.038 and 0.030 μg/mL, respectively.
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Sulfated sulfakinin
0 ImagesCat. No.: HY-P11156CAS No.: 172430-35-2Sulfated sulfakinin is a Sulfakinin receptor (SKR) activator with EC50s of 1.6 and 5.4 nM for Tribolium castaneumTc TcSKR1 and TcSKR2, respectively. SKRs are G-protein-coupled receptors (GPCRs) that interact with sulfakinins to modulate diverse biological processes. Sulfated sulfakinin can be used for tho control of pest insects research.
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Hirsutanonol
0 ImagesCat. No.: HY-N4044CAS No.: 41137-86-4Synonyms: (5S)-HirsutanonolHirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC50 value of 44.11 μg/mL for microfilariae.
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Cletoquine-d4-1
0 ImagesCat. No.: HY-135810S1CAS No.: 1216461-56-1Synonyms: Desethylhydroxychloroquine-d4-1Cletoquine-d4-1 is the deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment.
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2′′-Acetylastragalin
0 ImagesCat. No.: HY-N1716CAS No.: 1206734-95-32’’-Acetylastragalin (Compound 2) is a compound isolated from the aerial parts of Delphinium staphisagria, with an IC50 value of 6.5 μM for Vero cells. 2’’-Acetylastragalin has trypanoidal activity.
