Ser/Thr Protease Activator
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Alteplase
0 ImagesCat. No.: HY-108865CAS No.: 105857-23-6Synonyms: Actilyse; ActivaseAlteplase (Actilyse; Activase), a tissue plasminogen activator prepared by recombination, is a thrombolytic agent that play important roles in acute ischemic stroke, pulmonary embolism, acute myocardial infarction, and occluded catheters.
The product size below only indicate the effective content of Alteplase. The ratio of Alteplase effective content : total content = 1:46-1:50. The actual ratio depends on the batch.)
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LM2I
0 ImagesLM2I is a derivative of Spinosyn A (SPA). LM2I is argininosuccinate synthase (ASS1) enzyme activator, and tumor inhibitor that directly interact with ASS1. LM2I has significant antiproliferative activity in seven colorectal cancer cell-lines and xenograft tumors of colorectal cancer. LM2I inhibits colorectal cancer cell growth via the EGFR pathway.
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Sutacimig
0 ImagesSynonyms: HMB-001Sutacimig (HMB-001) is a humanized antibody of the (H-γ4_L-κ)_(H-γ4_L-κ) format that targets FⅦa/TREML1. One arm of Sutacimig binds to endogenous FVIIa, thereby prolonging the half-life of FVIIa and increasing its accumulation in the bloodstream, while the other arm binds to TLT-1, which is exclusively expressed on the surface of activated platelets. This localizes endogenous FVIIa to activated platelets, further enhancing the activity of FVIIa. Sutacimig enhances Thrombin generation, fibrin formation, and the formation of stable fibrin-platelet networks at sites of vascular injury. Sutacimig can be used in studies related to Glanzmann thrombasthenia.
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LZL50
0 ImagesCat. No.: HY-181764LZL50 is an orally effective human caseinolytic protease P (hClpP) activator with an EC50 of 0.29 μM. LZL50 activates hClpP, a serine protease that mediates mitochondrial quality control by degrading damaged or misfolded mitochondrial proteins. LZL50 exhibits antitumor activity in a breast cancer xenograft mouse model. LZL50 can be used in research related to breast cancer.
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RK-1205-I
0 ImagesCat. No.: HY-184894RK-1205-I is a protein phosphatase 2A (PP2A) inhibitor and fungal growth inhibitor. RK-1205-I inhibits PP2A activity in fungal cells, leading to the accumulation of Ser/Thr phosphorylated proteins. RK-1205-I acts as a morphoregulator and induces unique morphological changes in filamentous fungi. RK-1205-I inhibits the growth of various fungi, including Aspergillus oryzae, Aspergillus fumigatus and Candida auris. RK-1205-I can be used for the research of fungal infections.
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UK-356202
0 ImagesCat. No.: HY-129690CAS No.: 223671-94-1UK-356202 is a urokinase-type plasminogen activator (uPA) with a Ki value of 0.037 μM. UK-356202 can be used in research related to the topical treatment of chronic ulcerous wounds.
