2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. Aquaporin
  5. Aquaporin Modulator

Aquaporin Modulator

Aquaporin Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-W176557
    TGN-073
    		Modulator 99.53%
    TGN-073 is an orally active, blood-brain barrier-permeable aquaporin 4 (AQP4) modulator. TGN-073 increases the uptake and distribution of brain MRI tracers in the brain parenchyma and reduces the levels of insoluble amyloid β-40 and β-42. TGN-073 can be used in research related to Alzheimer's disease, dementia, traumatic brain injury and pain.
  • HY-N0237
    Atractyloside A
    		Modulator 98.11%
    Atractyloside A is an orally active inhibitor of the TLR4/MyD88/NF-κB signaling pathway and also an opener of the mitochondrial permeability transition pore (MPTP). Atractyloside A interferes with the activation of the TLR4/MyD88/NF-κB pathway, thereby inhibiting intestinal inflammatory responses. Atractyloside A reverses mucin synthesis impairment, improves intestinal barrier integrity, and restores homeostasis by altering the composition of the gut microbiota. Atractyloside A can be used in studies related to spleen deficiency diarrhea and myocardial injury.