Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Inhibitors
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Drug Derivative Related Products (4058)
Related Products (4058)
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7-Hydroxy-5,6,8,3',4'-pentamethoxyflavone
0 ImagesCat. No.: HY-N19780CAS No.: 149402-88-07-Hydroxy-5,6,8,3',4'-pentamethoxyflavone is a polymethoxyflavone compound. 7-Hydroxy-5,6,8,3',4'-pentamethoxyflavone can be synthesized from naringin and hesperidin.
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Prostaglandin A2 ethyl ester
0 ImagesCat. No.: HY-172817Prostaglandin A2 ethyl ester is an ethyl ester derivative of Prostaglandin A2 (HY-113041). Prostaglandin A2 ethyl ester exhibits vasodilatory activity and has a protective effect on the kidneys.
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1,10-Bis(methylsulfinyl)decane
0 ImagesCat. No.: HY-180384CAS No.: 28242-22-01,10-Bis(methylsulfinyl)decane (Compound IIf) is a decamethonium analogue and is a non-electrolytic sulfoxide compound. 1,10-Bis(methylsulfinyl)decane has low lethal (LD50 >37.5 mg/kg) effect in mice and neuromuscular blocking (ED50 >7 mg/kg) effects in cat.
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Nimolinone
0 ImagesCat. No.: HY-122043CAS No.: 106533-51-1Nimolinone is an active compound.
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7-(3'-Carboxybutoxy)coumarin
0 ImagesCat. No.: HY-N13771CAS No.: 16851-01-77-(3'-Carboxybutoxy)coumarin is a natural coumarin.
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Inonotusane A
0 ImagesCat. No.: HY-N17282CAS No.: 1889275-07-3Inonotusane A (Compound 1) is a lanostane-type triterpenoid compound found in the sclerotia of Inonotus obliquus.
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Reprimun
0 ImagesCat. No.: HY-126582CAS No.: 41776-67-4Reprimun is an active compound.
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Suffruticosol D
0 ImagesCat. No.: HY-N17055CAS No.: 1261292-11-8Suffruticosol D is a natural phenolic compound.
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Quercetin-7-O-gentiobisoside
0 ImagesCat. No.: HY-N17555CAS No.: 852617-04-0Quercetin-7-O-gentiobisoside is a natural product that can be found in locust tree.
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Forsythenside F
0 ImagesCat. No.: HY-N17402CAS No.: 1160755-73-6Forsythenside F is a natural product that can be found in Cornus officinalis Siebold & Zucc..
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Eriodictyol 7-O-methylglucuronide
0 ImagesCat. No.: HY-N13787CAS No.: 133360-42-6Eriodictyol 7-O-methylglucuronide is a natural flavonoid.
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4''-Acetyl-4-(a-L-Rhamnopyranosyloxy)-benzylglucosinolate
0 ImagesCat. No.: HY-N19689CAS No.: 549503-17-54''-Acetyl-4-(a-L-Rhamnopyranosyloxy)-benzylglucosinolate is a plant secondary metabolite that can be found in the leaves of Moringa oleifera and Moringa stenopetala. 4''-Acetyl-4-(a-L-Rhamnopyranosyloxy)-benzylglucosinolate can be used for research on cancer and inflammatory diseases.
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Epitrametol
0 ImagesCat. No.: HY-N16954CAS No.: 627538-65-2Epitrametol is a natural phenylacetylene.
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p-Hydroxyphenylethyl p-coumarate
0 ImagesCat. No.: HY-N17046CAS No.: 149030-02-4p-Hydroxyphenylethyl p-coumarate is a natural phenylacetylene.
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SW 71425
0 ImagesCat. No.: HY-107008CAS No.: 155990-20-8SW 71425 inhibits cell growth against breast, colon, non-small cell lung, and ovarian tumors..
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α-Isopropylaminohexanophenone hydrochloride
0 ImagesCat. No.: HY-170052CAS No.: 18296-61-2α-Isopropylaminohexanophenone hydrochloride is a drug derivative.
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Esculentoside T
0 ImagesCat. No.: HY-N2206CAS No.: 1346652-41-2Esculentoside T is a natural product that can be found in soybeans.
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Capilliposide C
0 ImagesCat. No.: HY-N17292CAS No.: 886467-46-5Capilliposide C is a natural product that can be found in Lysimachia capillipes?Hemsl..
