1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. HPPD
  4. HPPD Inhibitor

HPPD Inhibitor

HPPD Inhibitors (22):

Cat. No. Product Name Effect Purity
  • HY-135767
    Bicyclopyrone
    Inhibitor 99.95%
    Bicyclopyrone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (Hpd).
  • HY-137910
    Tembotrione
    Inhibitor 99.41%
    Tembotrione is a herbicide belonging to the HPPD (dioxygenase) inhibitor class with crop selectivity. Tembotrione effectively controls a variety of weeds including broadleaf and gramineous species by disrupting carotenoid synthesis, which leads to chlorophyll degradation and leaf whitening. Mixing Tembotrione with isoxaflutole or adding surfactants optimizes its efficacy and reduces phytotoxicity, with no residual impact on subsequent cruciferous crops, thus helping to increase maize grain yield. The activity of Tembotrione decreases under drought conditions, and under specific conditions (such as double-dose treatment), it may cause reversible yellowing and even yield reduction in crops such as poppy.
  • HY-114991
    Leptospermone
    Inhibitor 98.46%
    Leptospermone is a competitive, reversible inhibitor for p-Hydroxyphenylpyruvate dioxygenase (HPPD), with an IC50 of 12.1 μM. Leptospermone exhibits herbicidal activity for its bleaching effect.
  • HY-161308
    HPPD-IN-3
    Inhibitor 98.46%
    HPPD-IN-3 (compound 25) is a potent inhibitor of 4-Hydroxyphenylpyruvate dioxygenase (HPPD), with IC50 of 10 nM, more potency than Mesotrione (HY-12853).
  • HY-W725385
    Cypyrafluone
    Inhibitor 99.58%
    Cypyrafluone is a 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor that prevents the homogentisic acid (HGA) production. Cypyrafluone can control weed in wheat fields.
  • HY-116139
    Isoxaflutole
    Inhibitor 98.79%
    Isoxaflutole (Merlin) is the inhibitor for HPPD that blocks benzoquinone biosynthesis, and results in the bleaching of weeds. Isoxaflutole can be used as herbicide.
  • HY-163559
    HPPD-IN-4
    Inhibitor
    HPPD-IN-4 (Compound III-29) is a selective inhibitor of HPPD with anIC50 of 0.19 μM. HPPD-IN-4 is primarily used in the study of high-efficiency herbicides.
  • HY-155465
    HPPD-IN-2
    Inhibitor
    HPPD-IN-2 (compound 28) is a herbicide based on HPPD inhibitors. HPPD-IN-2 potently targets AtHPPD and exhibits enhanced safety in canola crops.
  • HY-155135
    HPPD-IN-1
    Inhibitor
    HPPD-IN-1 (compound II-3) is a HPPD inhibitor. HPPD-IN-1 shows inhibitory activity of Arabidopsis thaliana HPPD (AtHPPD) with an IC50 value of 0.248 μM, which was superior to that of mesotrione (HY-12853) (0.283 μM) in vitro. HPPD-IN-1 shows excellent herbicidal activity against broadleaf and monocotyledonous weeds.
  • HY-179006
    HPPD-IN-7
    Inhibitor
    HPPD-IN-7 (Compound 35) is an Arabidopsis thaliana HPPD inhibitor (IC50 of 89 nM) and herbicide. HPPD-IN-7 exhibits herbicidal activity against Digitaria sanguinalis, Amaranthus retroflexus, Chenopodium serotinum, Abutilon theophrasti, Setaria viridis.
  • HY-135767R
    Bicyclopyrone (Standard)
    Inhibitor
    Bicyclopyrone (Standard) is the analytical standard of Bicyclopyrone. This product is intended for research and analytical applications. Bicyclopyrone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (Hpd).
  • HY-175641
    HPPD-IN-6
    Inhibitor
    HPPD-IN-6 (Compound IIy) is a HPPD inhibitor with high rice selectivity. HPPD-IN-6 has potent herbicidal activities against Echinochloa crus-galli and Leymus chinensis, including the herbicide-resistant biotypes with EC50s of 19.62-33.26 g of ai/ha. HPPD-IN-6 effectively controls the weeds in rice fields at 90-150 g of ai/ha. HPPD-IN-6 can be used for the development of herbicide.
  • HY-116139R
    Isoxaflutole (Standard)
    Inhibitor
    Isoxaflutole (Standard) is the analytical standard of Isoxaflutole. This product is intended for research and analytical applications. Isoxaflutole (Merlin) is the inhibitor for HPPD that blocks benzoquinone biosynthesis, and results in the bleaching of weeds.
  • HY-170795
    AtHPPD-IN-1
    Inhibitor
    AtHPPD-IN-1 (Compound III-15) is an HPPD inhibitor and herbicide with high safety for peanuts. AtHPPD-IN-1 has IC50 of 12 nM for Arabidopsis thaliana HPPD.
  • HY-W753723
    Biscarfentrazone
    Inhibitor
    Biscarfentrazone is a HPPD-inhibiting herbicide for wheat fields, which can effectively control ALS-resistant broadleaf weeds and is safe to wheat.
  • HY-137910R
    Tembotrione (Standard)
    Inhibitor
    Tembotrione (Standard) is the analytical standard of Tembotrione. This product is intended for research and analytical applications. Tembotrione is a drug that may reduce the productivity of carrots. Tembotrione has the activity of reducing carrot stem mass. Tembotrione can be used to study the total productivity of carrot . Tembotrione is a herbicide belonging to the HPPD (dioxygenase) inhibitor class with crop selectivity. Tembotrione effectively controls a variety of weeds including broadleaf and gramineous species by disrupting carotenoid synthesis, which leads to chlorophyll degradation and leaf whitening. Mixing Tembotrione with isoxaflutole or adding surfactants optimizes its efficacy and reduces phytotoxicity, with no residual impact on subsequent cruciferous crops, thus helping to increase maize grain yield. The activity of Tembotrione decreases under drought conditions, and under specific conditions (such as double-dose treatment), it may cause reversible yellowing and even yield reduction in crops such as poppy.
  • HY-W727532
    Fenpyrazone
    Inhibitor
    Fenpyrazone is a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor as well as a post-emergence herbicide. By inhibiting the activity of HPPD, Fenpyrazone indirectly blocks carotenoid biosynthesis in plants, causing bleaching of new tissues in sensitive plants, followed by necrosis and eventual death. Fenpyrazone is used in studies on controlling annual monocotyledonous and dicotyledonous weeds in summer maize fields.
  • HY-W705486
    RPA 202248
    Inhibitor
    RPA 202248 is a p-hydroxy phenyl pyruvate dioxygenase (HPPD) inhibitor and degradation product of Isoxaflutole (HY-116139). RPA 202248 demonstrates environmental persistence and undergoes transport through soil matrix and macropores to subsurface drain flow in agricultural field settings.
  • HY-W1115537
    Flusulfinam
    Inhibitor
    Flusulfinam is a HPPD inhibitor and herbicide, with an IC50 of 0.0181 μM against Arabidopsis thaliana HPPD. Flusulfinam inhibits the catalytic activity of recombinant Arabidopsis thaliana HPPD. Flusulfinam exhibits potent herbicidal activity against barnyard grass (Echinochloa crus-galli). Flusulfinam inhibits the growth of Digitaria sanguinalis.
  • HY-W753209
    Tolpyralate
    Inhibitor
    Tolpyralate is a selective post-emergence herbicide and corn Herbicide. Tolpyralate inhibits 4-HPPD. Tolpyralate exhibits herbicidal activity against a variety of weeds, including the glyphosate-resistant weed Amaranthus tuberculatus.