1. Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
  2. Reactive Oxygen Species
  3. Mesotrione

Mesotrione 

Cat. No.: HY-12853
Handling Instructions

Mesotrione is a herbicide belongs to the benzoylcyclohexanedione family. Mesotrione is a potent and competitive and reversible inhibitor of HPPD enzyme. Mesotrione is selective to maize due to rapid metabolism and relative high tolerance by the susceptible crop plant.

For research use only. We do not sell to patients.

Mesotrione Chemical Structure

Mesotrione Chemical Structure

CAS No. : 104206-82-8

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Description

Mesotrione is a herbicide belongs to the benzoylcyclohexanedione family. Mesotrione is a potent and competitive and reversible inhibitor of HPPD enzyme. Mesotrione is selective to maize due to rapid metabolism and relative high tolerance by the susceptible crop plant[1].

IC50 & Target

Target: HPPD enzyme[1]

In Vitro

Mesotrione is a potent HPPD enzyme inhibitor, giving an estimated Ki value in the range 6±18pM at 25°C. HPPD is from Arabidopsis thaliana (L)[1].

In Vivo

Mesotrione (oral administration; 1 mg/kg; single dose) is rapidly and extensively absorbed in rats and mice. After a single dose, the urinary excretione is estimated, the urinary excretione estimated absorption values ranged from 62.2% in males and 68.3% in females. The mean peak blood concentration (Cmax) of radioactivity occurred 0.5 hours after dosing in each sex[1].

Molecular Weight

339.32

Formula

C₁₄H₁₃NO₇S

CAS No.

104206-82-8

SMILES

O=C1C(C(C2=CC=C(S(=O)(C)=O)C=C2[N+]([O-])=O)=O)C(CCC1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

MesotrioneReactive Oxygen SpeciesMaize,4-hydroxyphenylpyruvateHPPDbroad-leaved weedsgrass weedsDigitariaEchinochloaInhibitorinhibitorinhibit

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Mesotrione
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HY-12853
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