567-75-9
Chemical Structure
Leptospermone
- CAS No.: 567-75-9
- Formula:C15H22O4
- Molecular Weight:266.33
IUPAC Name: 2,2,4,4-tetramethyl-6-(3-methylbutanoyl)cyclohexane-1,3,5-trione
InChIKey: YDWYMAHAWHBPPT-UHFFFAOYSA-N
SMILES: O=C1C(C)(C(C(C)(C(C1C(CC(C)C)=O)=O)C)=O)C
Biological Activity: Leptospermone is a competitive, reversible inhibitor for p-Hydroxyphenylpyruvate dioxygenase (HPPD), with an IC50 of 12.1 μM. Leptospermone exhibits herbicidal activity for its bleaching effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Leptospermone | 98.46% | Leptospermone is a competitive, reversible inhibitor for p-Hydroxyphenylpyruvate dioxygenase (HPPD), with an IC50 of 12.1 μM. Leptospermone exhibits herbicidal activity for its bleaching effect. | ||||||||||||||||||||
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M50054 (Standard) | ≥98% | M50054 (Standard) is the analytical standard of M50054. This product is intended for research and analytical applications. M50054 is a potent inhibitor of apoptosis. M50054 inhibits Etoposide-induced caspase-3 activation of U937 cells with an IC50 of 79 μg/mL. M50054 does not directly inhibit the enzymatic activity of caspase-3. M50054 can be used for the research anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia. | ||||||||||||||||||||
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Curdione (Standard) | ≥98% | Curdione (Standard) is the analytical standard of Curdione. This product is intended for research and analytical applications. Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC50 = 1.1 μM) and cyclooxygenase 2 expression. | ||||||||||||||||||||
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cis-Dihydroepitodomatuic acid | ||||||||||||||||||||||
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(1'S,6'R)-4-(2',2',6'-Trimethyl-6'-vinylcyclohexyl)-2-butanone | ||||||||||||||||||||||
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Neocurdione | Neocurdione is a hepatoprotective sesquiterpene isolated from Curcuma zedoaria rhizome. Neocurdione exerts potent effect on D-galactosamine- (D-Gain) and lipopolysaccharide- (LPS) induced acute liver injury in mice. | |||||||||||||||||||||
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Bisabola-2,10-diene-1,9-dione | Bisabola-2,10-diene-1,9-dione is a Triterpenoids product that can be isolated from the leaves of Alpinia intermedia. | |||||||||||||||||||||
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Bisabola-3,10-dien-2-one | Bisabola-3,10-dien-2-one (1-Bisabolone) is a Phenylpropanoids product that can be isolated from the heartwoods of Cassia garrettiana. | |||||||||||||||||||||
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(+)-3-(Trifluoroacetyl)camphor | (+)-3-(Trifluoroacetyl)camphor is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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Dihydroartemisinin diketo aldehyde | Dihydroartemisinin diketo aldehyde is an Artemether (HY-N0402) impurity. | |||||||||||||||||||||
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