HPV
Human papillomavirus
Human papillomavirus (HPV) is the most common sexually transmitted infection (STI) that commonly causes skin or mucous membrane growths (warts). HPV is a virus with double-stranded circular DNA from the papillomavirus family. All HPVs have icosahedral capsids. HPV displays tropism toward the epithelial basal layer, which houses adult epithelial stem cells responsible for replenishing the epithelium with daughter cells. There are more than 100 varieties of human papillomavirus (HPV). Some types of HPV infection cause warts, and some (HPV 16 and 18) can cause different types of cancer, including cancers of the anus, penis, vagina, vulva and back of the throat (oropharyngeal). Worldwide, the risk of being infected at least once in a lifetime among both men and women is 50%. Vaccines can help protect against the strains of HPV most likely to cause genital warts or cervical cancer.
All Product Categories
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HPV Related Products (41)
Related Products (41)
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Recombinant Proteins (4)
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Vorinostat-d5
0 ImagesSynonyms: SAHA-d5; Suberoylanilide hydroxamic acid-d5Vorinostat-d5 (SAHA-d5) is the deuterium labeled Vorinostat. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification.
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Teslexivir
0 ImagesCat. No.: HY-109045CAS No.: 1075798-37-6Synonyms: BTA074; AP 611074Teslexivir (BTA074) is a potent antiviral agent. Teslexivir is a potent and selective inhibitor of the interaction between two essential viral proteins, E1 and E2, an association that is a necessary step in the DNA replication and thus viral production for Human Papilloma Virus (HPV) 6 and 11. Teslexivir can be used for condyloma research.
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Epetirimod
0 ImagesCat. No.: HY-14741CAS No.: 227318-71-0Synonyms: S-30563; TAK-851
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HPV18-IN-1
0 ImagesCat. No.: HY-146033CAS No.: 331851-78-6HPV18-IN-1 (Compound H1) is a potent inhibitor of HPV18. HPV18-IN-1 prevents cervical cancer cells from premature cell procession and abnormal proliferation. HPV18-IN-1 supresses E7-Rb-E2F cellular pathway and DNA methylation. HPV18-IN-1 has the potential for the research of cancer diseases.
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Hydroxymycotrienin B
0 ImagesCat. No.: HY-N15103CAS No.: 178550-62-4Hydroxymycotrienin B is an ansamycin group antibiotic (triene-ansamycin) found in culture broths of Bacillus sp. BMJ958-62F4. Hydroxymycotrienin B inhibits HPV-positive cervical cancer cell growth 3~10 times more strongly than HPV-negative cervical cancer cells. Hydroxymycotrienin B can be used for the research of human cervical cancer.
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Afovirsen
0 ImagesCat. No.: HY-177610CAS No.: 151356-08-0Synonyms: ISIS 2105
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E6AP-mimicking peptide
0 ImagesCat. No.: HY-P10428E6AP-mimicking peptide (compound 13) is a high-affinity, selective, irreversible and potent peptide-based covalent HPV16 E6 inhibitor targeting the 16E6 oncoprotein using a cysteine-reactive acrylamide warhead. E6AP-mimicking peptide has a Ki of 17 nM. E6AP-mimicking peptide targets all residues appearing in the binding pocket of E6 to disrupt the binding interface of 16E6 and E6AP. E6AP-mimicking peptide selectively binds and crosslinks to MBP-16E6 in PBS or a protein mixture.
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GS-9191
0 ImagesCat. No.: HY-119151CAS No.: 859209-84-0GS-9191 is the prodrug of the nucleotide analog PMEG. GS-9191 is a topical agent to permeate skin and be metabolized to the active nucleoside triphosphate analog in the epithelial layer. GS-9191 inhibits NA synthesis, arrests cell in S phase, and induces cell apoptosis. GS-9191 can be used for research of human papillomaviruses (HPV) infection.
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Protein E7(43-62)
0 ImagesCat. No.: HY-P2299CAS No.: 143853-58-1Protein E7(43-62) is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein).
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HPV16 E7 (86-93)
0 ImagesCat. No.: HY-P1778CAS No.: 160212-93-1HPV16 E7 (86-93) is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide. HPV16 E7 (86-93) is immunogenic in cervical carcinomas.
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Human α-defensin 5
0 ImagesCat. No.: HY-P5694Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC50: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity.
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HPV16-E711-20 epitope
0 ImagesCat. No.: HY-P1881CAS No.: 160040-04-0HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. HPV16 CTL epitopes may be good candidates for the development of an effective peptide-based antitumor vaccine.
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Afovirsen sodium
0 ImagesCat. No.: HY-177610ACAS No.: 138330-98-0Synonyms: ISIS 2105 sodium
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Anti-HPV18 L1 Antibody (H18L1-A)
0 ImagesCat. No.: HY-P991215Anti-HPV18 L1 Antibody (H18L1-A) is a humanized antibody targeting the L1 protein of human papillomavirus type 18 (HPV18). Anti-HPV18 L1 Antibody (H18L1-A) blocks the binding of the HPV18 virus to cell surface receptors, neutralizing the virus activity, and thus inhibiting the virus from infecting cells. Anti-HPV18 L1 Antibody (H18L1-A) is promising for research of human papillomavirus-related diseases.
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Larixyl acetate (Standard)
0 ImagesCat. No.: HY-101795RCAS No.: 4608-49-5Larixyl acetate (Standard) is the analytical standard of Larixyl acetate. This product is intended for research and analytical applications. Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction.
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JD-13
0 ImagesCat. No.: HY-184394CAS No.: 2969172-58-3JD-13 is a HPV-1 inhibitor and anti-proliferative agent against cancer cells. JD-13 downregulates the expression of HSV-1 DNA polymerase-related genes UL30 and UL42, and inhibits viral replication. JD-13 induces apoptosis (apoptosis) in colorectal cancer cells and suppresses their colony formation. JD-13 can be applied to the research of herpes simplex virus infection and related diseases including colorectal cancer, lung cancer, esophageal cancer and breast cancer.
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GSK984
0 ImagesCat. No.: HY-129253CAS No.: 827591-04-8GSK984 is an inactive control probe for GSK983 (HY-119098), a dihydroorotate dehydrogenase (DHODH) inhibitor with antiviral activity.
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Inosine pranobex (Standard)
0 ImagesSynonyms: Imunovir (Standard); Delimmun (Standard); Groprinosin (Standard); (Standard)Inosine pranobex (Standard) is the analytical standard of Inosine pranobex. This product is intended for research and analytical applications. Inosine pranobex is an orally active immunomodulator. Inosine pranobex has broad-spectrum antiviral activity. Inosine pranobex inhibits human immunodeficiency virus (HIV), herpes simplex virus (HSV), vaccinia virus (VACV), human tumor virus (HPV), Cytomegalovirus, influenza virus (INFV), parainfluenza virus (PIV), and Epstein-Barr virus
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Teslexivir hydrochloride (Standard)
0 ImagesCat. No.: HY-109045ARCAS No.: 1075281-70-7Synonyms: BTA074 hydrochloride (Standard); AP 611074 hydrochloride (Standard)Teslexivir hydrochloride (Standard) is the analytical standard of Teslexivir (hydrochloride) (HY-109045A). This product is intended for research and analytical applications. Teslexivir (BTA074) hydrochloride is a potent antiviral agent. Teslexivir hydrochloride is a potent and selective inhibitor of the interaction between two essential viral proteins, E1 and E2, an association that is a necessary step in the DNA replication and thus viral production for Human Papilloma Virus (HPV) 6 and 11. Teslexivir hydrochloride can be used for condyloma research.
