Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1266)
Related Products (1266)
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31hP
0 ImagesCat. No.: HY-17195131hP is an asymmetric A3 lipid. 31hP can facilitate in vivo luciferase expression. 31hP can be rapidly degraded in the presence of esterase owing to two biocleavable ester bonds. 31hP can be used in the synthesis of lipid nanoparticles (LNPs).
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DOIC
0 ImagesCat. No.: HY-142999CAS No.: 1292821-06-7DOIC is a cationic lipid that can be used for RNA vaccines.
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Si5-N14
0 ImagesCat. No.: HY-165603CAS No.: 3006860-57-4Si5-N14 is a key component of siloxane-incorporated lipid nanoparticles (SiLNP), possessing pro-vascular repair and anti-tumor activities. In the transgenic GFP mouse model, Si5-N14 can mediate CRISPR-Cas9 editing. In the Lewis lung carcinoma (LLC) tumor-bearing mouse model, Si5-N14 can knock out the expression of Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) to exert an anti-tumor effect. In a mouse model of lung injury induced by viral infection, the delivery of Fibroblast Growth Factor-2 (FGF-2) mRNA via Si5-N14 can promote vascular repair, increase blood oxygen levels, and improve lung function. Si5-N14 shows promise for research in the fields of oncology, pneumonia, and cardiovascular diseases.
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(2S)-3-Keto sphinganine (d6:0) hydrochloride
0 ImagesCat. No.: HY-165975CAS No.: 1314999-30-8Synonyms: (2S)-3-Keto-C6-dihydrosphingosine hydrochloride(2S)-3-Keto sphinganine (d6:0) ((2S)-3-Keto-C6-dihydrosphingosine) hydrochloride is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
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DSPE-PEG1000-Biotin
0 ImagesCat. No.: HY-140736ACAS No.: 385437-57-0DSPE-PEG1000-Biotin is a biotin-labeled PEG derivative composed of phospholipid (DSPE), a hydrophilic polyethylene glycol chain (PEG1000) and a biotin tag. DSPE-PEG1000-Biotin is widely used in scientific research for constructing targeted liposomes, micelles and lipid nanoparticles for drug delivery and cell binding experiments.
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PEG5000-C-DMG
0 ImagesCat. No.: HY-W1049124ACAS No.: 1443687-74-8PEG5000-C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468). PEG5000-C-DMG can be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of siRNA.
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Mal-PEG12-DSPE
0 ImagesCat. No.: HY-140957CAS No.: 2413909-83-6
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Q1-ALC-0315 iodide
0 ImagesCat. No.: HY-172329CAS No.: 3112713-48-8
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06:0 PG sodium
0 ImagesCat. No.: HY-157684CAS No.: 322647-18-706:0 PG sodium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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C14-SPM
0 ImagesCat. No.: HY-160569CAS No.: 2241864-59-3C14-SPM is a polyamine branched-chain lipidoid that can be used for the delivery of siRNA.
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mPEG2000-DLG
0 ImagesCat. No.: HY-179911CAS No.: 1793050-71-1mPEG2000-DLG is a PEG-based lipid that can be used to formulate lipid nanoparticles for drug delivery.
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DMPA
0 ImagesCat. No.: HY-177193CAS No.: 28874-52-4Synonyms: 1,2-Dimyristoyl-sn-glycero-3-phosphate; 1,2-Dimyristoyl-PADMPA (1,2-Dimyristoyl-sn-glycero-3-phosphate; 1,2-Dimyristoyl-PA) is a phospholipid that can be used for preparing liposomes. DMPA, when used as a negatively charged lipid component in fluid liposomes, supports liposome-bacterium fusion. DMPA can be used in the research of drug delivery.
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DMPE-PEG750 ammonium
0 ImagesCat. No.: HY-155926CAS No.: 474922-82-2Synonyms: 14:0 PEG750 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammoniumDMPE-PEG750 ammonium (14:0 PEG750 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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rac-3-Hexadecanamido-2-methoxypropan-1-ol phosphocholine hydrate
0 ImagesCat. No.: HY-W779204CAS No.: 163751-35-7rac-3-Hexadecanamido-2-methoxypropan-1-ol Phosphocholine Monohydrate is a phospholipid and an inhibitor of Protein kinase C.
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DSPE-PEG4000-OH
0 ImagesCat. No.: HY-164720DSPE-PEG4000-OH is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG4000-OH can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research.
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DMHAPC-Chol
0 ImagesCat. No.: HY-125734CAS No.: 774598-29-7DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA.
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16:0 PDP PE
0 ImagesCat. No.: HY-W719862CAS No.: 474944-16-616:0 PDP PE belongs to a class of head group modified functionalized lipids. 16:0 PDP PE has been used in preparation of rhodamine high-density lipoprotein nanoparticle (Rh-HDL NP) synthesis.
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Cholesterol n-Octanoate
0 ImagesCholesterol n-Octanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and caprylic acid. Cholesterol n-octanoate has various applications in the pharmaceutical industry, notably as a bioactive compound with potential research potential to improve a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
