2. Signaling Pathways
  3. Others
  4. mRNA

mRNA

messenger RNA

 

mRNA Related Products (326):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-174660
    Human IFNL1 mRNA
    Human IFNL1 mRNA encodes the human interferon lambda 1 (IFNL1) protein, a cytokine distantly related to type I interferons and the IL-10 family. IFNL1 plays a critical role in the antiviral host defense, predominantly in the epithelial tissues.
    Human IFNL1 mRNA
  • HY-174484
    OVA mRNA (5moU)
    OVA mRNA (5moU) encodes the ovalbumin (OVA) protein, a member of the serpin superfamily and the predominant glycoprotein found in egg whites. It is a commonly used antigen for immunization and biochemical studies and is an established model allergen for airway hyper-responsiveness.
    OVA mRNA (5moU)
  • HY-174658
    Human IFNL3 mRNA
    Human IFNL3 mRNA encodes the human interferon lambda 3 (IFNL3) protein, a cytokine distantly related to type I interferons and the IL-10 family. IFNL3 plays a critical role in the antiviral host defense, predominantly in the epithelial tissues.
    Human IFNL3 mRNA
  • HY-174643
    Human IL11RA mRNA
    Human IL11RA mRNA encodes the human interleukin 11 receptor subunit alpha (IL11RA) protein, a member of the hematopoietic cytokine receptor family. IL11RA is essential for the normal development of craniofacial bones and teeth.
    Human IL11RA mRNA
  • HY-174534
    Human TGFB1 mRNA
    Human TGFB1 mRNA encodes the human transforming growth factor beta 1 (TGFB1) protein, a secreted ligand of the TGF-beta superfamily. TGFB1 can regulate cell proliferation, differentiation and growth, and also play a role in modulating expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha.
    Human TGFB1 mRNA
  • HY-174496
    eGFP mRNA (5moU)
    eGFP mRNA (5moU) expresses a green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. EGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence. The substitution with 5’-Methoxyuridine (5moU) improves protein expression and reduces innate immune response.
    eGFP mRNA (5moU)
  • HY-174670
    Human HGF mRNA
    Human HGF mRNA encodes the human hepatocyte growth factor (HGF) protein, a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. It also plays a role in angiogenesis, tumorogenesis, and tissue regeneration.
    Human HGF mRNA
  • HY-174522
    Human TLR6 mRNA
    Human TLR6 mRNA encodes the human toll like receptor 6 (TLR6) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins.
    Human TLR6 mRNA
  • HY-174519
    Human TLR9 mRNA
    Human TLR9 mRNA encodes the human toll like receptor 9 (TLR9) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR9 mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
    Human TLR9 mRNA
  • HY-174626
    Human IL1R1 mRNA
    Human IL1R1 mRNA encodes the human interleukin 1 receptor type 1 (IL1R1) protein, a cytokine receptor that belongs to the interleukin-1 receptor family. IL1R1 is an important mediator involved in many cytokine-induced immune and inflammatory responses.
    Human IL1R1 mRNA
  • HY-174613
    Human IL27 mRNA
    Human IL27 mRNA encodes the human interleukin 27 (IL27) protein, one of the subunits of a heterodimeric cytokine complex. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity and induce isotype switching in B-cells.
    Human IL27 mRNA
  • HY-174573
    Human NEUROD1 mRNA
    Human NEUROD1 mRNA encodes the human neuronal differentiation 1 (NEUROD1)protein, a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. NEUROD1 forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box.
    Human NEUROD1 mRNA
  • HY-112905
    AN11736
    		Inhibitor
    AN11736 is a CPSF3 inhibitor. AN11736 exerts a potent anti-trypsin effect by specifically inhibiting the activity of the trypanosome CPSF3 endonuclease, disrupting the mRNA maturation process. AN11736 exhibits IC50s against T. congolense and T. vivax of 0.14 and 1.3 nM, respectively. AN11736 exhibits strong anti-trypsin activity in mouse and cattle models.
    AN11736
  • HY-174535
    Human TGFA mRNA
    Human TGFA mRNA encodes the human transforming growth factor alpha (TGFA) protein. TGFA is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development.
    Human TGFA mRNA
  • HY-174714
    Human FAS mRNA
    Human FAS mRNA encodes the human Fas cell surface death receptor (FAS) protein, a member of the TNF-receptor superfamily. FAS has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system.
    Human FAS mRNA
  • HY-174608
    Human IL32 mRNA
    Human IL32 mRNA encodes the human interleukin 32 (IL32) protein, a member of the cytokine family. IL32 induces the production of TNFalpha from macrophage cells.
    Human IL32 mRNA
  • HY-174675
    Human GATA3 mRNA
    Human GATA3 mRNA encodes the human GATA binding protein 3 (GATA3) which belongs to the GATA family. GATA3 is an important regulator of T-cell development. It also plays an important role in endothelial cell biology.
    Human GATA3 mRNA
  • HY-174549
    Human PDGFRA mRNA
    Human PDGFRA mRNA encodes the human platelet derived growth factor receptor alpha (PDGFRA) protein, a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA may play a role in organ development, wound healing, and tumor progression.
    Human PDGFRA mRNA
  • HY-174780
    Human AMHR2 mRNA
    Human AMHR2 mRNA encodes the human anti-Mullerian hormone receptor type 2 (AMHR2) protein, a receptor for the anti-Mullerian hormone (AMH).
    Human AMHR2 mRNA
  • HY-174566
    Human NRG2 mRNA
    Human NRG2 mRNA encodes the human neuregulin 2 (NRG2) protein, a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, NRG2 can induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.
    Human NRG2 mRNA