2. Signaling Pathways
  3. GPCR/G Protein
  4. PTHR
  5. PTHR Inhibitor

PTHR Inhibitor

PTHR Isoform Comparison

PTHR Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-16498
    Tigapotide
    		Inhibitor
    Tigapotide (PCK-3145) is a synthetic 15-mer peptide derived from prostate-secretory protein, and acts as an antineoplastic agent. Tigapotide inhibits tumor growth, experimental bone metastasis, and malignancy-associated hypocalcemia. Tigapotide induces apoptosis in prostate cancer cells and tumors, and suppresses the growth of prostate cancer cells. Tigapotide inhibits the production of parathyroid hormone-related protein (PTHrP) in tumors and plasma. Tigapotide reduces plasma calcium levels in hypercalcemic tumor-bearing rats. Tigapotide is applicable for the research of prostate cancer and malignancy-associated hypercalcemia.