2. Signaling Pathways
  3. GPCR/G Protein
  4. PTHR
  5. PTH1R Isoform
  6. PTH1R Antagonist

PTH1R Antagonist

PTH1R Antagonists (4):

Cat. No. Product Name Effect Purity
  • HY-P4385
    (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat)
    		Antagonist 99.77%
    (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist and does not display any partial agonist activity.
  • HY-113918
    SW-106
    		Antagonist
    SW-106 is a selective antagonist of parathyroid hormone/parathyroid hormone-related peptide receptor (PPR) and PTHR1, with an IC50 value of 0.99 μM against PPR. SW-106 antagonizes cAMP responses. SW-106 can be used in the research of osteoporosis.
  • HY-186200
    PTHR1 antagonist 1
    		Antagonist
    PTHR1 antagonist 1 (Compound 18) is a PTHR1 antagonist with an IC50 of 0.090 µM. PTHR1 antagonist 1 is applicable to the research of calcium metabolism disorders.
  • HY-131206
    DS37571084
    		Antagonist
    DS37571084 is an orally active and potent antagonist of the parathyroid hormone type 1 receptor (PTHR1), with an IC50 value of 0.17 μM. DS37571084 can be used for the study of hyperparathyroidism.