2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Ser/Thr Kinase
  5. Ser/Thr Kinase Inducer

Ser/Thr Kinase Inducer

Ser/Thr Kinase Inducer (1):

Cat. No. Product Name Effect Purity
  • HY-151574
    PfGSK3/PfPK6-IN-1
    		Inducer 99.38%
    PfGSK3/PfPK6-IN-1 is a dual Plasmodium serine/threonine kinase inhibitor, with an IC50 of 97 nM against PfGSK3 and 8 nM against PfPK6 of Plasmodium falciparum. PfGSK3/PfPK6-IN-1 inhibits the proliferation of blood-stage parasites of Plasmodium falciparum 3D7. PfGSK3/PfPK6-IN-1 shows low cytotoxicity to hepatocytes at a concentration of 200 nM, and reduces cell viability at a concentration of 2 μM. PfGSK3/PfPK6-IN-1 is applicable to malaria-related research.