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Cat. No.: HY-107677

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A 844606

Name: A 844606
Brand: MedChemExpress
SKU: HY-107677
Price: 400.00 USD
Availability: InStock
Rating: 5 (1 reviews)

A 844606 is a highly potent and selective α4β2 nAChR agonist. A 844606 can be used in the study of schizophrenia, Huntington's disease, Alzheimer's disease, and Parkinson's disease.

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CAS No.: 861119-08-6
화학식: C₂₀H₂₀N₂O₂
분자량:320.39

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

A 844606 Chemical Structure

CAS No.: 861119-08-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

A 844606 is a highly potent and selective α4β2 nAChR agonist. A 844606 can be used in the study of schizophrenia, Huntington's disease, Alzheimer's disease, and Parkinson's disease^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>100 μM Compound: 52	Agonist activity at human recombinant alpha3beta4 nAChR in HEK293 cells by FLIPR assay Agonist activity at human recombinant alpha3beta4 nAChR in HEK293 cells by FLIPR assay	[PMID: 22281189]
HEK293	EC₅₀	>100 μM Compound: 52	Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assay Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assay	[PMID: 22281189]
Oocyte	EC₅₀	2.2 μM Compound: 52	Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assay Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assay	[PMID: 22281189]

Chemical Information

CAS No. 861119-08-6
분자량 320.39
화학식 C₂₀H₂₀N₂O₂
SMILES

O=C1C2=C(OC3=CC=C(N4CC5CN(CC5C4)C)C=C31)C=CC=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Leung K. 2-(5-[11C]Methyl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-xanthene-9-one. 2010 Oct 12 [updated 2011 Jan 19]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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A 844606

Dihydro-β-erythroidine hydrobromide

PHA-543613

SEN12333

PNU-282987

AR-R17779 hydrochloride

Cotinine

Varenicline

A-582941 dihydrochloride

MG624

GTS-21 dihydrochloride

α-Bungarotoxin

Myosmine

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

A 844606

Dihydro-β-erythroidine hydrobromide

PHA-543613

SEN12333

PNU-282987

AR-R17779 hydrochloride

Cotinine

Varenicline

A-582941 dihydrochloride

MG624

GTS-21 dihydrochloride

α-Bungarotoxin

Myosmine

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

A 844606 Related Classifications

HY-107677 Related Classifications

Bioz