AChE-IN-106
AChE-IN-106 is an AChE inhibitor. AChE-IN-106 shows no obvious cytotoxicity at low concentrations. AChE-IN-106 can be used for the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C13H9Cl2NO2S
- Molecular Weight:314.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AChE |
AChE-IN-106 (Compound 6j) (0-500 μM; 24 h) shows good safety in SH-SY5Y cells[1].
AChE-IN-106 (15.62 μM; 24 h) potently inhibits AChE activity in Aβ-induced SH-SY5Y cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SH-SY5Y human neuroblastoma cells
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Concentration:0, 15.62, 31.25, 62.5, 125, 250 and 500 μM
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Incubation Time:24 h
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Result:Maintained 96.138% cell viability relative to untreated controls at 15.62 μM.
Decreased viability in a dose-dependent manner to 89.631% at 31.25 μM, 84.379% at 62.5 μM, 79.899% at 125 μM, 65.012% at 250 μM, and 42.035% at 500 μM.
Chemical Information
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Molecular Weight 314.19
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Formula C13H9Cl2NO2S
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SMILES
CC(C1=C(C)N=C(C(C2=CC(Cl)=CC=C2Cl)=O)S1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AChE-IN-106 Related Classifications
HY-181119 Related Classifications
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