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AChE-IN-72

AChE-IN-72 (Compound 13a) is an inhibitor for acetylcholinesterase (AChE) with an IC50 of 0.59 μM. AChE-IN-72 inhibits BChE with an IC50 of 5.02 μM. AChE-IN-72 exhibits radical scavenging with IC50 of 5.88 μM. AChE-IN-72 exhibits iron-chelating property, inhibits Aβ1−42 aggregation, and inhibits NLRP3 inflammasome activation. AChE-IN-72 ameliorates memory impairment in Betaine (HY-B0710)-induced AD mouse model. AChE-IN-72 is blood-brain barrier (BBB) penetrable.

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  • Formula: C24H25N3O4
  • Molecular Weight:419.47
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AChE-IN-72 Chemical Structure
    AChE-IN-72 Chemical Structure
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All Cholinesterase (ChE) Isoforms

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100 mg

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    AChE-IN-72 Chemical Structure
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  • AChE-IN-72