Aldicarb sulfoxide
Based on 1 Customer Validation
Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC50 of 10 μM for both in zebrafish.
For research use only. We do not sell to patients.
- Purity: 98.41%
- CAS No.: 1646-87-3
- Formula: C7H14N2O3S
- Molecular Weight:206.26
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 10 μM (zebrafish ChE); IC50: 10 μM (zebrafish CaE)[2]
Aldicarb sulfoxide (10 μg/ml; 24 h) decreases the glutathione (GSH) concentration in CHO-K1 cells by 13.34%[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione reductase (GR) activity in CHO-K1 cells by 101%[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione peroxidase (GPx) activity increased in CHO-K1 cells by 32%[1].
Aldicarb sulfoxide (0.2-300 μM, 48 h) induces the increase of heart rate at low and decrease at higher concentration in zebrafish embryos[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1646-87-3
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Appearance Solid
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Molecular Weight 206.26
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Formula C7H14N2O3S
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Color White to off-white
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SMILES
CC(C)(/C=N/OC(NC)=O)S(C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 100 mg/mL (484.82 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (623 KB)
- English - EN (623 KB)
- Français - FR (623 KB)
- Deutsch - DE (623 KB)
- Norwegian - NO (623 KB)
- Español - ES (623 KB)
- Swedish - SV (623 KB)
- Italian - IT (623 KB)
- Korean - KR (623 KB)
- Portuguese - PT (623 KB)
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Handling Instructions (2659 KB)
References
[1]. Maran E, et al. Effects of four carbamate compounds on antioxidant parameters. Ecotoxicol Environ Saf. 2009 Mar;72(3):922-30. [Content Brief]
[2]. Küster E, Altenburger R. Suborganismic and organismic effects of aldicarb and its metabolite aldicarb-sulfoxide to the zebrafish embryo (Danio rerio). Chemosphere. 2007 Jun;68(4):751-60. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.8482 mL | 24.2412 mL | 48.4825 mL | 121.2062 mL |
| 5 mM | 0.9696 mL | 4.8482 mL | 9.6965 mL | 24.2412 mL | |
| 10 mM | 0.4848 mL | 2.4241 mL | 4.8482 mL | 12.1206 mL | |
| 15 mM | 0.3232 mL | 1.6161 mL | 3.2322 mL | 8.0804 mL | |
| 20 mM | 0.2424 mL | 1.2121 mL | 2.4241 mL | 6.0603 mL | |
| 25 mM | 0.1939 mL | 0.9696 mL | 1.9393 mL | 4.8482 mL | |
| 30 mM | 0.1616 mL | 0.8080 mL | 1.6161 mL | 4.0402 mL | |
| 40 mM | 0.1212 mL | 0.6060 mL | 1.2121 mL | 3.0302 mL | |
| 50 mM | 0.0970 mL | 0.4848 mL | 0.9696 mL | 2.4241 mL | |
| 60 mM | 0.0808 mL | 0.4040 mL | 0.8080 mL | 2.0201 mL | |
| 80 mM | 0.0606 mL | 0.3030 mL | 0.6060 mL | 1.5151 mL | |
| 100 mM | 0.0485 mL | 0.2424 mL | 0.4848 mL | 1.2121 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Aldicarb sulfoxide Related Classifications
HY-124104 Related Classifications
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