Aldicarb sulfoxide

Name: Aldicarb sulfoxide
Brand: MedChemExpress
SKU: HY-124104
Rating: 4.5 (1 reviews)

Cat. No.: HY-124104 Purity: 98.41%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC₅₀ of 10 μM for both in zebrafish.

For research use only. We do not sell to patients.

Aldicarb sulfoxide Chemical Structure

CAS No. : 1646-87-3

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Aldicarb sulfoxide:

Aldicarb sulfoxide-d₃ Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

IC50: 10 μM (zebrafish ChE); IC50: 10 μM (zebrafish CaE)^[2]

In Vitro

Aldicarb sulfoxide (10 μg/ml; 24 h) decreases the glutathione (GSH) concentration in CHO-K1 cells by 13.34%^[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione reductase (GR) activity in CHO-K1 cells by 101%^[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione peroxidase (GPx) activity increased in CHO-K1 cells by 32%^[1].
Aldicarb sulfoxide (0.2-300 μM, 48 h) induces the increase of heart rate at low and decrease at higher concentration in zebrafish embryos^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

206.26

Formula

C₇H₁₄N₂O₃S

CAS No.

1646-87-3

Appearance

Solid

Color

White to off-white

SMILES

CC(C)(/C=N/OC(NC)=O)S(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (484.82 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8482 mL	24.2412 mL	48.4825 mL
5 mM	0.9697 mL	4.8482 mL	9.6965 mL
10 mM	0.4848 mL	2.4241 mL	4.8482 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.41%

Select Batch:

Data Sheet (271 KB) SDS (623 KB)

COA (246 KB) LCMS (325 KB)

Handling Instructions (2659 KB)

References

[1]. Maran E, et al. Effects of four carbamate compounds on antioxidant parameters. Ecotoxicol Environ Saf. 2009 Mar;72(3):922-30. [Content Brief]

[2]. Küster E, Altenburger R. Suborganismic and organismic effects of aldicarb and its metabolite aldicarb-sulfoxide to the zebrafish embryo (Danio rerio). Chemosphere. 2007 Jun;68(4):751-60. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.8482 mL	24.2412 mL	48.4825 mL	121.2062 mL
	5 mM	0.9696 mL	4.8482 mL	9.6965 mL	24.2412 mL
	10 mM	0.4848 mL	2.4241 mL	4.8482 mL	12.1206 mL
	15 mM	0.3232 mL	1.6161 mL	3.2322 mL	8.0804 mL
	20 mM	0.2424 mL	1.2121 mL	2.4241 mL	6.0603 mL
	25 mM	0.1939 mL	0.9696 mL	1.9393 mL	4.8482 mL
	30 mM	0.1616 mL	0.8080 mL	1.6161 mL	4.0402 mL
	40 mM	0.1212 mL	0.6060 mL	1.2121 mL	3.0302 mL
	50 mM	0.0970 mL	0.4848 mL	0.9696 mL	2.4241 mL
	60 mM	0.0808 mL	0.4040 mL	0.8080 mL	2.0201 mL
	80 mM	0.0606 mL	0.3030 mL	0.6060 mL	1.5151 mL
	100 mM	0.0485 mL	0.2424 mL	0.4848 mL	1.2121 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.