2. Apoptosis
  3. Ferroptosis
  4. AMB8LK

AMB8LK is a human monoclonal antibody targeting H-ferritin, with specificity for tumor-associated heterologous ferritin. AMB8LK specifically recognizes and binds to H-ferritin overexpressed on the surface of tumor cells. AMB8LK can be used in research related to cancer and immune diseases.

For research use only. We do not sell to patients.

AMB8LK

AMB8LK Chemical Structure

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AMB8LK Related Antibodies

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Description

AMB8LK is a human monoclonal antibody targeting H-ferritin, with specificity for tumor-associated heterologous ferritin. AMB8LK specifically recognizes and binds to H-ferritin overexpressed on the surface of tumor cells. AMB8LK can be used in research related to cancer and immune diseases[1].

Species Reactivity

Human
In Vitro

AMB8LK is a human monoclonal antibody targeting H-ferritin, the functional core subunit of ferritin. H-ferritin forms a 24-mer nanocage together with light chains, and is the only subunit with ferroxidase activity, responsible for converting toxic Fe2+ into non-toxic Fe3+ for storage. Meanwhile, it is deeply associated with NF‑κB, inflammation and ferroptosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AMB8LK Related Antibodies
Gene ID

94033  [NCBI]

Accession

Q8N4E7
Target

Ferritin
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AMB8LK Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AMB8LKFerroptosisH-ferritinrefractory hodgkin’s diseasebreast carcinomatumor-associated isoferritinspancreas cancerlung (nsclc) cancerpancreatic adenocarcinomatumor cellsCAPAN-1SK-BR3Inhibitorinhibitorinhibit

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