Amine-PEG6-thiol hydrochloride
Based on 1 Customer Validation
Amine-PEG6-thiol hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Formula: C14H32ClNO6S
- Molecular Weight:377.92
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Viscous Liquid
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Molecular Weight 377.92
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Formula C14H32ClNO6S
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SMILES
SCCOCCOCCOCCOCCOCCOCCN.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 350 mg/mL (926.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6461 mL | 13.2303 mL | 26.4606 mL | 66.1516 mL |
| 5 mM | 0.5292 mL | 2.6461 mL | 5.2921 mL | 13.2303 mL | |
| 10 mM | 0.2646 mL | 1.3230 mL | 2.6461 mL | 6.6152 mL | |
| 15 mM | 0.1764 mL | 0.8820 mL | 1.7640 mL | 4.4101 mL | |
| 20 mM | 0.1323 mL | 0.6615 mL | 1.3230 mL | 3.3076 mL | |
| 25 mM | 0.1058 mL | 0.5292 mL | 1.0584 mL | 2.6461 mL | |
| 30 mM | 0.0882 mL | 0.4410 mL | 0.8820 mL | 2.2051 mL | |
| 40 mM | 0.0662 mL | 0.3308 mL | 0.6615 mL | 1.6538 mL | |
| 50 mM | 0.0529 mL | 0.2646 mL | 0.5292 mL | 1.3230 mL | |
| 60 mM | 0.0441 mL | 0.2205 mL | 0.4410 mL | 1.1025 mL | |
| 80 mM | 0.0331 mL | 0.1654 mL | 0.3308 mL | 0.8269 mL | |
| 100 mM | 0.0265 mL | 0.1323 mL | 0.2646 mL | 0.6615 mL |
Amine-PEG6-thiol hydrochloride Related Classifications
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