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Amivantamab (FUT8-KO)

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Based on 1 Customer Validation

Amivantamab (FUT8-KO) is an anti-EGFR-MET monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Amivantamab (FUT8-KO) inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells.

For research use only. We do not sell to patients.

  • Purity: 98%
  • Molecular Weight:145.88 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Amivantamab (FUT8-KO)
  • Experimental Validation Results for Amivantamab (FUT8-KO)
  • Amivantamab (FUT8-KO) Chemical Structure
    Amivantamab (FUT8-KO) Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Other Forms of Amivantamab (FUT8-KO):

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Loaded Amivantamab (FUT8-KO) on ProA biosensor, can bind EGFR Protein, Human (621a.a, HEK293, His, HY-P70613) with an affinity constant of 2.774E-08 M as determined in BLI assay.

  • Amivantamab (FUT8-KO) Chemical Structure
    1/16
  • Amivantamab (FUT8-KO)
  • Loaded Amivantamab (FUT8-KO) on ProA biosensor, can bind EGFR Protein, Human (621a.a, HEK293, His, HY-P70613) with an affinity constant of 2.774E-08 M as determined in BLI assay.
  • IgG1-kappa