1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. AMP-PNP tetralithium

AMP-PNP tetralithium (Synonyms: Adenylyl-imidodiphosphate tetralithium)

Cat. No.: HY-128933
Handling Instructions

AMP-PNP tetralithium (Adenylyl-imidodiphosphate tetralithium) is a non-hydrolysable analogue of ATP and inhibits KATP channels.

For research use only. We do not sell to patients.

AMP-PNP tetralithium Chemical Structure

AMP-PNP tetralithium Chemical Structure

CAS No. : 72957-42-7

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Description

AMP-PNP tetralithium (Adenylyl-imidodiphosphate tetralithium) is a non-hydrolysable analogue of ATP and inhibits KATP channels[1][2].

In Vitro

AMP-PNP (5 to 500 μM; Li salt) reduced the open-probability po of KATP channels and decreases the single-channel currents at high nucleotide concentrations by approximately 10%[2].
AMP-PNP inhibits KATP channels of ventricular myocytes and of pancreatic β-cells both in the absence and presence of Mg2+ ions[2].

Molecular Weight

529.93

Formula

C₁₀H₁₃Li₄N₆O₁₂P₃

CAS No.

72957-42-7

SMILES

O[[email protected]]1[[email protected]](N2C3=C(N=C2)C(N)=NC=N3)O[[email protected]@H]([[email protected]]1O)COP(OP(NP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

AMP-PNP tetralithiumAdenylyl-imidodiphosphate tetralithiumPotassium ChannelKcsAInhibitorinhibitorinhibit

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