1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. AMP-PNP tetralithium

AMP-PNP tetralithium  (Synonyms: Adenylyl-imidodiphosphate tetralithium)

Cat. No.: HY-128933 Purity: ≥97.0%
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AMP-PNP tetralithium (Adenylyl-imidodiphosphate tetralithium) is a non-hydrolysable analogue of ATP and inhibits KATP channels.

For research use only. We do not sell to patients.

AMP-PNP tetralithium Chemical Structure

AMP-PNP tetralithium Chemical Structure

CAS No. : 72957-42-7

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Description

AMP-PNP tetralithium (Adenylyl-imidodiphosphate tetralithium) is a non-hydrolysable analogue of ATP and inhibits KATP channels[1][2].

In Vitro

AMP-PNP (5 to 500 μM; Li salt) reduced the open-probability po of KATP channels and decreases the single-channel currents at high nucleotide concentrations by approximately 10%[2].
AMP-PNP inhibits KATP channels of ventricular myocytes and of pancreatic β-cells both in the absence and presence of Mg2+ ions[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

529.93

Formula

C10H13Li4N6O12P3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@H](N2C3=C(N=C2)C(N)=NC=N3)O[C@@H]([C@H]1O)COP(OP(NP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: ≥97.0%

References
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AMP-PNP tetralithium Related Classifications

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AMP-PNP tetralithium
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