Anti-CD44 Antibody (Hermes-1)
Based on 2 publication(s) in Google Scholar
Anti-CD44 Antibody (Hermes-1) is a kind of rat IgG2a κ chimeric antibody, targeting to human CD44. Anti-CD44 Antibody (Hermes-1) blocks the binding of hyaluronan to CD44. Anti-CD44 Antibody (Hermes-1) restores (Platelet-derived Growth Factor-BB)-induced β-receptor activation and motility in fibroblasts. Anti-CD44 Antibody (Hermes-1) causes partial loss of the anti-aging effect of hyaluronic.
For research use only. We do not sell to patients.
- Purity: ≥95.0%
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Anti-CD44 Antibody (Hermes-1)
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Biological Activity
Rat IgG2a kappa
Human
CD44
Anti-CD44 Antibody (Hermes-1) (10 μg/mL, 12 h) increases SA-β-Gal-positive cells in human amniotic epithelial stem cells (hAECs)[1].
Anti-CD44 Antibody (Hermes-1) (25-50 μg/mL, 27 h) restores (Platelet-derived Growth Factor-BB)-induced β-receptor activation and motility in fibroblasts[2].
Anti-CD44 Antibody (Hermes-1) (50 μg/mL, 3 h) neutralizes the inhibitory effect of hyaluronan on PDGF-BB (Platelet-derived Growth Factor-BB)-induced β-receptor phosphorylation in fibroblasts[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
in vivo CD44 blockade in xenografts; in vitro CD44 blockade; Western blot; Immunofluorescence
Chemical Information
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Appearance Liquid
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Molecular Weight 150 kDa
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Color Colorless to light yellow
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SMILES
[Anti-CD44 Antibody (Hermes-1)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Commun
Magnetically triggered thermoelectric heterojunctions with an efficient magnetic-thermo-electric energy cascade conversion for synergistic cancer therapy. [Abstract]2025 Mar 10;16(1):2369. PMID: 40064895 -
Biomaterials
A biocompatible copper based therapeutic nanoplatform for CD44 specific tumor targeted therapy and potent immune reprogramming. [Abstract]2026 Jun 13:335:124373. PMID: 42314235
Purity & Documentation
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Data Sheet (261 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Yu C, et al. Hyaluronan delays human amniotic epithelial stem cell senescence by regulating CD44 isoform switch to activate AKT/mTOR signals. Biomed Pharmacother. 2024 Jan;170:116100. [Content Brief]
[2]. Li L, et al. Inhibition of platelet-derived growth factor-BB-induced receptor activation and fibroblast migration by hyaluronan activation of CD44. J Biol Chem. 2006 Sep 8;281(36):26512-9. [Content Brief]
[3]. Zhao C, et al. The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44. Oncotarget. 2019 Nov 12;10(61):6561-6576. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-CD44 Antibody (Hermes-1) Related Classifications
HY-P990859 Related Classifications
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