Anti-IL-13 Antibody (C836)
Based on 1 Customer Validation
Anti-IL-13 Antibody (C836) is a neutralizing monoclonal antibody targeting human IL-13. The Fab fragment of Anti-IL-13 Antibody (C836) is a heterodimer composed of heavy chains and light chains, each folded into variable and constant domains. Anti-IL-13 Antibody (C836) can be used for chronic inflammatory diseases, such as asthma.
For research use only. We do not sell to patients.
- Purity: 97.20%
- Molecular Weight:48.22 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Fab (IgG1-CH1-EPKSC)-His
Human
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IL-13 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
ELISA, FACS, Functional assay
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Immobilized IL-13-hFc can bind Anti-IL-13 Antibody (C836) . The EC50 for this effect is 36.74 ng/mL.
Chemical Information
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Appearance Liquid
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Molecular Weight 48.22 kDa
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Color Colorless to light yellow
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SMILES
N/A
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (257 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Obmolova G, et al. Promoting crystallization of antibody-antigen complexes via microseed matrix screening. Acta Crystallogr D Biol Crystallogr. 2010 Aug;66(Pt 8):927-33. [Content Brief]
[2]. Bagnasco D, et al. A Critical Evaluation of Anti-IL-13 and Anti-IL-4 Strategies in Severe Asthma. Int Arch Allergy Immunol. 2016;170(2):122-31. [Content Brief]
[3]. Teplyakov A, et al. Antigen recognition by antibody C836 through adjustment of V(L)/V(H) packing. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1165-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)