Anti-inflammatory agent 48
Anti-inflammatory agent 48 is an anti-inflammatory agent based on its role in inhibiting the NF-κB signaling pathway and activating HO-1 expression.
For research use only. We do not sell to patients.
- Formula: C24H21Cl2NO3
- Molecular Weight:442.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Anti-inflammatory agent 48 (compound 1) shows NO-inhibitory ability in LPS-induced RAW 264.7 macrophage cells. Anti-inflammatory agent 48 exhibits superior NF-κB-inhibitory ability compared to Diclofenac through the activation of Nrf2/HO-1 signaling pathway in RAW 264.7[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 442.33
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Formula C24H21Cl2NO3
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SMILES
ClC1=CC=CC(Cl)=C1NC2=CC=CC=C2CC(OC3=C(OC)C=C(CC=C)C=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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