1. Immunology/Inflammation
  2. STING NO Synthase
  3. Anti-inflammatory agent 65

Anti-inflammatory agent 65 (compound 29) is a Hederagonic acid derivative with potent anti-inflammatory activity. Anti-inflammatory agent 65 inhibits nitric oxide (NO) release. Anti-inflammatory agent 65 inhibits the nuclear translocation of IRF3 and p65, and disrupts the STING/IRF3/NF-κB signaling pathway, thereby attenuating the inflammatory response.

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Anti-inflammatory agent 65

Anti-inflammatory agent 65 Estructura química

No. CAS : 3035442-58-8

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Descripciòn

Anti-inflammatory agent 65 (compound 29) is a Hederagonic acid derivative with potent anti-inflammatory activity. Anti-inflammatory agent 65 inhibits nitric oxide (NO) release. Anti-inflammatory agent 65 inhibits the nuclear translocation of IRF3 and p65, and disrupts the STING/IRF3/NF-κB signaling pathway, thereby attenuating the inflammatory response[1].

Peso molecular

834.22

Fòrmula

C49H71NO6S2

No. CAS
SMILES

C[C@@]1(COC(CCCNC(CCCC[C@H]2SSCC2)=O)=O)C(CC[C@]3(C)[C@@]4([H])CC=C5[C@]6([H])CC(C)(C)CC[C@@](C(OCC7=CC=CC=C7)=O)6CC[C@](C)5[C@@](C)4CC[C@@]13[H])=O

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Room temperature in continental US; may vary elsewhere.

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Nombre del producto:
Anti-inflammatory agent 65
Cat. No.:
HY-149724
Cantidad:
MCE Japan Authorized Agent: