Anterior Gradient 2 Antibody (YA3577)(PBS only)
(Synonyms: AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116)Anterior Gradient 2 Antibody (YA3577) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Anterior Gradient 2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
ICC/IF, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
Anterior Gradient 2 Antibody (YA3577) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Anterior Gradient 2.
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Host Mouse
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 20 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 20 kDa
Purified recombinant fragment of human AGR2 (AA: 21-175) expressed in E. Coli.
affinity purified.
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Anterior Gradient 2 is required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion[1].
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Subcellular Localization
Secreted; Endoplasmic reticulum
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Expression
Tissue_specificity:It is highly expressed in the trachea, lungs, stomach, colon, prostate, and small intestine. It is lowly expressed in the pituitary gland, salivary glands, mammary glands, bladder, appendix, ovary, fetal lungs, uterus, pancreas, kidneys, fetal kidneys, testes, placenta, thyroid gland, and estrogen receptor (ER) positive breast cancer cell lines. -
Subunit
Monomer and homodimer (PubMed:23274113). Interacts with LYPD3 and DAG1 (alphaDAG1) (PubMed:12592373). Interacts with MUC2; disulfide-linked (PubMed:19359471, PubMed:34237462)
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SwissProt ID
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Synonyms
AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116
Documentation
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