Ataxin 2 Antibody
(Synonyms: ATX2, SCA2, TNRC13, ATXN2, Ataxin-2, Spinocerebellar ataxia type 2 protein, Trinucleotide repeat-containing gene 13 protein)Ataxin 2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Ataxin 2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
Ataxin 2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Ataxin 2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 170 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 140 kDa
Synthetic peptide corresponding to the center region of human Ataxin 2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Ataxin 2 is involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. -
Isoforms & Post-Translational Modification
Ataxin 2 has 5 isoforms, Q99700-1: amino acid length is 1313, molecular weight is 140283 Da (predicted); Q99700-2: amino acid length is 995, molecular weight is 106048 Da (predicted); Q99700-3: amino acid length is 258, molecular weight is 27894 Da (predicted); Q99700-4: amino acid length is 1243, molecular weight is 132884 Da (predicted); Q99700-5: amino acid length is 1006, molecular weight is 109037 Da (predicted).
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Subunit
Monomer (By similarity).
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SwissProt ID
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Synonyms
ATX2, SCA2, TNRC13, ATXN2, Ataxin-2, Spinocerebellar ataxia type 2 protein, Trinucleotide repeat-containing gene 13 protein
Documentation
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