ATPIF1 Antibody (YA4562)(PBS only)
(Synonyms: IP; ATPI; ATPIP)ATPIF1 Antibody (YA4562) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to ATPIF1.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P, ICC/IF, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:100-1:500 | 1:200-1:400 | 1:10000 |
Product Details
ATPIF1 Antibody (YA4562) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to ATPIF1.
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Host Mouse
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 12 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 12 kDa
Purified recombinant fragment of human ATPIF1 (AA: 1-106) expressed in E. Coli.
affinity purified.
Non-conjugated
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ATPIF1 is an Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme
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Subcellular Localization
Mitochondrion
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Isoforms & Post-Translational Modification
Q9UII2 has 3 isomers: Q9UII2-1: 12249 Da (predicted); Q9UII2-2: 7912 Da (predicted); Q9UII2-3: 6592 Da (predicted).
Exhibits variability in chain length, mitochondria have distinct pools of protein cleaved after the 24th, 25th, and 26th amino acid -
Subunit
Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0 (By similarity)
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SwissProt ID
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Synonyms
IP; ATPI; ATPIP
Documentation
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