BTLA Antibody (YA1364)

製品番号: HY-P81619: データシート SDS COA User Guide for Antibodies
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BTLA Antibody (YA1364) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to BTLA.

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容量	価格（税別）	在庫状況	数量
10 μL	$180	在庫あり	Estimated Time of Arrival: December 31
50 μL	$462	在庫あり	Estimated Time of Arrival: December 31
100 μL	$738	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

BTLA Antibody (YA1364) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to BTLA.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 33 kDa;

Observed band size: 33 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q7Z6A9

Gene ID

151888 [NCBI]

Immunogen

Recombinant human BTLA protein

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:50-1:100
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	純度	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044)

Subcellular Localization：Cell membrane; Single-pass type I membrane protein

Isoforms & Post-Translational Modification：Q7Z6A9 has 2 isomers: Q7Z6A9-1: 32834 Da (predicted); Q7Z6A9-2: 27317 Da (predicted).
Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11;N-glycosylated

Subunit：Interacts with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006). Interacts with TNFRSF14/HVEM (via cysteine-rich domain 1) (PubMed:15568026, PubMed:18193050, PubMed:19915044)

RRID

AB_3103729

Database

Entrez Gene: 151888 Human

SwissProt: Q7Z6A9 Human

OMIM: 607925 Human

Research Field

Immunology

Synonyms

BTLA; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD antigen CD272

ドキュメンテーション

Select Batch:

データシート (232 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)