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CD137/4-1BB Antibody (YA4200)

(Synonyms: TNFRSF9; ILA; 4-1BB; CDw137)
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CD137/4-1BB Antibody (YA4200) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD137/4-1BB.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    WB, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS with 0.05% sodium azide

  • Conjugation:
    Non-conjugated
  • CD137/4-1BB Antibody (YA4200) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:200-1:400 1:10000

Product Details

Description

CD137/4-1BB Antibody (YA4200) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD137/4-1BB.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 35 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 28 kDa
Immunogen

Purified recombinant fragment of human CD137 (AA: 214-255) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS with 0.05% sodium azide

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CD137/4-1BB receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable)

  • Subcellular Localization

    Cell membrane; Single-pass type I membrane protein

  • Expression


    Tissue_specificity:Expressed on the surface of activated T cells

  • Subunit

    Interacts with TRAF1, TRAF2 and TRAF3 (PubMed:9418902, PubMed:9607925). Interacts with LRR-repeat protein 1/LRR-1 (PubMed:11804328)

  • SwissProt ID

    Q07011

  • Gene ID
    3604 [NCBI]
  • Synonyms

    TNFRSF9; ILA; 4-1BB; CDw137

CD137/4-1BB Antibody (YA4200) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CD137/4-1BB Antibody (YA4200) Product Image