CD172b Antibody (YA3485)
(Synonyms: SIRPB1; SIRP-BETA-1)CD172b Antibody (YA3485) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD172b.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:50-1:200 | 1:200-1:400 | 1:10000 |
Product Details
CD172b Antibody (YA3485) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD172b.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 48 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 43.2 kDa
Purified recombinant fragment of human CD172b (AA: extra 72-309) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD172b is an Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Also participates in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP[1].
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Detected in monocytes and dendritic cells -
Isoforms & Post-Translational Modification
O00241 has 3 isomers: O00241-1: 43211 Da (predicted); O00241-2: 19394 Da (predicted); Q5TFQ8-1: 43359 Da (predicted).
N-glycosylated -
Subunit
Homodimer; disulfide-linked. Interacts with TYROBP. This interaction results in the recruitment of SYK
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SwissProt ID
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Synonyms
SIRPB1; SIRP-BETA-1
Documentation
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