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Cat. No.: HY-P811364

CD20 Antibody

(Synonyms: Bp35, MS4A1)

CD20 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CD20.

For research use only. We do not sell to patients.

Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

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Quantity

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	FC FC: Flow Cytometry	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:500-2000	1μg /Test	1:5000-10000

Description

CD20 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CD20.

Host Rabbit
Clonality Polyclonal
Species Reactivity
Mouse Predicted Reactivity: Human,Rat

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
Observed Molecular Weight

Observed band size: 43 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 43 kDa

Sensitivity

Endogenous

Purification

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Solution
Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:12920111, PubMed:3925015, PubMed:7684739). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:12920111, PubMed:18474602, PubMed:7684739)
Subcellular Localization

Cell membrane; Multi-pass membrane protein; Cell membrane; Lipid-anchor
Expression

Tissue_specificity:Expressed on B cells
Isoforms & Post-Translational Modification

P11836 has 2 isomers: P11836-1: 33077 Da (predicted); P11836-2: 14581 Da (predicted).
Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate
Subunit

Forms homotetramers (PubMed:18474602, PubMed:7684739). Interacts with the heavy and light chains of cell surface IgM, the antigen-binding components of the BCR (PubMed:18474602)
Gene ID

931 [NCBI]
Synonyms

Bp35, MS4A1
Research Field

Cell biology