CD32B Antibody (YA4679)
(Synonyms: CD32 antibody; CD32 antigen antibody; CD32B antibody; CDw32 antibody; Fc fragment of IgG; low affinity II; receptor for; CD32; antibody; Fc fragment of IgG; low affinity IIb; receptor antibody; Fc fragment of IgG; low affinity IIb; receptor; CD32; antibody; Fc fragment of IgG; low affinity IIb; receptor for; CD32; antibody; Fc fragment of IgG; low affinity IIb; receptor for antibody; Fc gamma receptor IIB antibody; Fc gamma RII antibody; Fc gamma RIIB antibody; Fc-gamma RII antibody; Fc-gamma RII-b antibody; Fc-gamma-RIIb antibody; FCG2 antibody; FCG2B_HUMAN antibody; Fcgr2 antibody; FCGR2B antibody; FCRII antibody; FcRII-b antibody; IGFR2 antibody; IgG Fc receptor II beta antibody; IgG Fc receptor II-b antibody; Low affinity immunoglobulin gamma Fc region receptor II antibody; Low affinity immunoglobulin gamma Fc region receptor II-b antibody; Ly-17 antibody; Lym 1 antibody; Lymphocyte antigen 17 antibody; CD32 nanobody; )CD32B Antibody (YA4679) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD32B.
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Host:
Mouse
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Application:
ELISA, FC
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Reactivity :
Human
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Formulation:
Supplied in Phosphate-buffered solution.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:5000-100000 | 1-2μg/Test |
Product Details
CD32B Antibody (YA4679) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD32B.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Purified recombinant Human CD32
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Solution
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Formulation
Supplied in Phosphate-buffered solution.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD32B is a receptor for the Fc region of immunoglobulin G complexes or aggregates. A low-affinity receptor, CD32B is involved in various effector and regulatory functions, such as the phagocytosis of immune complexes and the regulation of B cell antibody production. Binding of CD32B to this receptor leads to the regulation of cellular activation previously triggered by antigen receptors (BCRs) on B cells, antigen receptors (TCRs) on T cells, or other Fc receptors. The IIB1 isoform does not mediate endocytosis or phagocytosis. The IIB2 isoform does not trigger phagocytosis.
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:It is the most widely distributed Fcγ receptor. It is expressed on monocytes, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B cells, platelets, and placental (endothelial cells) . It has not been detected in natural killer cells. -
Isoforms & Post-Translational Modification
CD32B has 5 isomers: P31994-1: 34044 Da (predicted); P31994-2: 31944 Da (predicted); P31994-3: 33450 Da (predicted); P31994-4: 33973 Da (predicted); P31994-5: 31873 Da (predicted).
Phosphorylated by the SRC-type Tyr-kinases LYN and BLK -
Subunit
Interacts with INPP5D/SHIP1. Interacts with FGR. Interacts with LYN
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SwissProt ID
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Synonyms
CD32 antibody; CD32 antigen antibody; CD32B antibody; CDw32 antibody; Fc fragment of IgG; low affinity II; receptor for; CD32; antibody; Fc fragment of IgG; low affinity IIb; receptor antibody; Fc fragment of IgG; low affinity IIb; receptor; CD32; antibody; Fc fragment of IgG; low affinity IIb; receptor for; CD32; antibody; Fc fragment of IgG; low affinity IIb; receptor for antibody; Fc gamma receptor IIB antibody; Fc gamma RII antibody; Fc gamma RIIB antibody; Fc-gamma RII antibody; Fc-gamma RII-b antibody; Fc-gamma-RIIb antibody; FCG2 antibody; FCG2B_HUMAN antibody; Fcgr2 antibody; FCGR2B antibody; FCRII antibody; FcRII-b antibody; IGFR2 antibody; IgG Fc receptor II beta antibody; IgG Fc receptor II-b antibody; Low affinity immunoglobulin gamma Fc region receptor II antibody; Low affinity immunoglobulin gamma Fc region receptor II-b antibody; Ly-17 antibody; Lym 1 antibody; Lymphocyte antigen 17 antibody; CD32 nanobody;
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