CD34 Antibody (YA3935)
CD34 Antibody (YA3935) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD34.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
WB, FC, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:400 | 1:10000 |
Product Details
CD34 Antibody (YA3935) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD34.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 120 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 41 kDa
Purified recombinant fragment of human CD34 (AA: extra 32-290) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD34 is a highly glycosylated type I transmembrane mucin-like glycoprotein and a surface marker of hematopoietic stem cells and hematopoietic progenitor cells. CD34 is mainly involved in stem cell adhesion, migration, self-renewal, and bone marrow homing, and participates in angiogenesis in vascular endothelial cells. CD34 is widely used in hematopoietic stem cell transplantation, immunophenotyping of acute leukemia, flow cytometry sorting, and tumor microvessel density detection.
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:It is selectively expressed on hematopoietic progenitor cells and small vascular endothelial cells in various tissues. -
Isoforms & Post-Translational Modification
CD34 has 2 isomers: P28906-1: 40716 Da (predicted); P28906-2: 35011 Da (predicted).
Highly glycosylated;Phosphorylated on serine residues by PKC -
SwissProt ID
Documentation
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