CD42a Antibody (YA3796)
(Synonyms: GPIX,GP9)CD42a Antibody (YA3796) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD42a.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P, FC, ELISA
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
CD42a Antibody (YA3796) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD42a.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 26 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 19 kDa
Purified recombinant fragment of human CD42A (AA: extra(17-147)) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD42a is a platelet membrane glycoprotein encoded by the GP9 gene and is an important component of the GPIb-IX-V complex. CD42a is mainly expressed in platelets and megakaryocytes. Although it does not directly bind to vWF, it is crucial for the stable expression and normal function of the complex. CD42a participates in the initial adhesion of platelets to damaged blood vessel walls and is a key early molecule in the hemostatic response. CD42a is an important pathogenic protein associated with Bernard-Soulier syndrome and is also a commonly used biomarker in megakaryocyte differentiation, AML-M7 immunophenotyping, and platelet function testing.
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Isoforms & Post-Translational Modification
CD42a: 177 amino acids, molecular weight 19046 Da.
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Subunit
Two GP-Ib beta are disulfide-linked to one GP-Ib alpha
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SwissProt ID
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Synonyms
GPIX,GP9
Documentation
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