CD89 Antibody (YA1960)
(Synonyms: FCAR; CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89)Based on 1 Customer Validation
CD89 Antibody (YA1960) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD89.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, IP, FC
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Reactivity :
Human
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Formulation:
Supplied in rabbit IgG in PBS(pH 7.4), 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
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FC
FC: Flow Cytometry
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:50-1:200 | 1:50-1:200 | 1:50 | 1:50-1:100 |
Product Details
CD89 Antibody (YA1960) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD89.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 70 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 32 kDa
A synthesized peptide derived from human CD89 aa240-287/287.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in rabbit IgG in PBS(pH 7.4), 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD89 binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Secreted; Secreted
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Expression
Tissue_specificity:Subtypes A.1, A.2, and A.3 are differentially expressed in blood and mucosal myeloid cells. Subtypes A.1, A.2, and A.3 are expressed in monocytes. Subtypes A.1 and A.2 are expressed in alveolar macrophages; however, only one subtype is expressed on the surface of alveolar macrophages. -
Isoforms & Post-Translational Modification
P24071 has 11 isomers: P24071-1: 32265 Da (predicted); P24071-2: 29683 Da (predicted); P24071-3: 21694 Da (predicted); P24071-4: 26996 Da (predicted); P24071-5: 25656 Da (predicted); P24071-6: 32629 Da (predicted); P24071-7: 19593 Da (predicted); P24071-8: 23394 Da (predicted); P24071-9: 20354 Da (predicted); P24071-10: 30925 Da (predicted); P24071-11: 28343 Da (predicted).
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Subunit
Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2
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SwissProt ID
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Synonyms
FCAR; CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89
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Research Field
Immunology
Documentation