CLIC1 Antibody (YA2807)

Cat. No.: HY-P83062: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

CLIC1 Antibody (YA2807) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CLIC1.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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CLIC1 Antibody (YA2807) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CLIC1 Antibody (YA2807) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CLIC1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 27 kDa;

Observed band size: 27 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

O00299

Gene ID

1192 [NCBI]

Immunogen

Recombinant protein of human CLIC1

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100
FC FC: Flow Cytometry	1:200-1:500
IP IP: Immunoprecipitation	1:20-1:50

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduces selenite and dehydroascorbate and may act as an antioxidant during oxidative stress response (PubMed:25581026, PubMed:37759794). Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Involved in regulation of the cell cycle

Subcellular Localization：Nucleus; Nucleus membrane; Single-pass membrane protein; Cytoplasm; Cell membrane; Single-pass membrane protein; Endoplasmic reticulum

Expression：
Tissue_specificity:Expression is prominent in heart, placenta, liver, kidney and pancreas

Subunit：Monomer. Homodimer (in vitro). Interacts with TRAPPC2. Dimerization requires a conformation change that leads to the exposure of a large hydrophobic surface. In vivo, this may lead to membrane insertion. Interacts with AKAP9

Database

Entrez Gene: 1192 Human ; 114584 Mouse ; 406864 Rat

SwissProt: O00299 Human ; Q9Z1Q5 Mouse ; Q6MG61 Rat

OMIM: 602872 Human

Research Field

Signal Transduction

Synonyms

Chloride intracellular channel protein 1; Chloride channel ABP; Nuclear chloride ion channel 27; NCC27; Regulatory nuclear chloride ion channel protein; hRNCC

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

CLIC1 Antibody (YA2807) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CLIC1 Antibody (YA2807)

CLIC1 Antibody (YA2807) Featured Recommendations:

Product Detail

Background

Documentation

CLIC1 Antibody (YA2807) Related Classifications

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