country

Change Language

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-P85107

Cripto1/CRIPTO Antibody (YA4799)

(Synonyms: TDGF1; CRIPTO; Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1)

Cripto1/CRIPTO Antibody (YA4799) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cripto1/CRIPTO.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:500-1:2000	1:10000

Description

Cripto1/CRIPTO Antibody (YA4799) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cripto1/CRIPTO.

Immunogen

Purified recombinant fragment of human Cripto expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953)
Subcellular Localization

Cell membrane; Lipid-anchor, GPI-anchor; Secreted
Expression

Tissue_specificity:This gene is preferentially expressed in gastric and colorectal cancers compared to normal tissues. It is also expressed in breast and lung cancers.
Subunit

Interacts with the activin type-1 receptor ACVR1B
SwissProt ID

P13385
Gene ID

6997 [NCBI]
Synonyms

TDGF1; CRIPTO; Teratocarcinoma-derived growth factor 1; Cripto-1 growth factor; CRGF; Epidermal growth factor-like cripto protein CR1